ID A0A4V5PAH6_MONMO Unreviewed; 1299 AA.
AC A0A4V5PAH6;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Bromodomain and PHD finger containing 3 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=EI555_016482 {ECO:0000313|EMBL:TKC49550.1};
OS Monodon monoceros (Narwhal) (Ceratodon monodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Monodon.
OX NCBI_TaxID=40151 {ECO:0000313|EMBL:TKC49550.1, ECO:0000313|Proteomes:UP000308365};
RN [1] {ECO:0000313|Proteomes:UP000308365}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=31054839; DOI=10.1016/j.isci.2019.03.023;
RA Westbury M.V., Petersen B., Garde E., Heide-Jorgensen M.P., Lorenzen E.D.;
RT "Narwhal Genome Reveals Long-Term Low Genetic Diversity despite Current
RT Large Abundance Size.";
RL IScience 15:592-599(2019).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TKC49550.1}.
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DR EMBL; RWIC01000115; TKC49550.1; -; Genomic_DNA.
DR Proteomes; UP000308365; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd05512; Bromo_brd1_like; 1.
DR CDD; cd15572; PHD_BRPF; 1.
DR CDD; cd20158; PWWP_BRPF3; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR019542; Enhancer_polycomb-like_N.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF19; BROMODOMAIN AND PHD FINGER-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF10513; EPL1; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00249; PHD; 2.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000308365};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 280..330
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 334..455
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 690..741
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 1142..1225
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 1..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 456..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 844..1081
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 634..661
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 7..31
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..191
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..503
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 899..928
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..951
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 958..977
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1004..1018
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1033..1056
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1057..1081
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:TKC49550.1"
SQ SEQUENCE 1299 AA; 145759 MW; 815A115E8DB9DB37 CRC64;
RRRPGRGPSA GREGARRWPR RSAREEAALR SPGRADLLGG RPARAQEPRT TGSLLASSLG
LSRWFPGAMR KPRRKSRQNA EGRRSPSPYS LKCSPTRETL TYAQAQRIVE VDIDGRLHRI
SIYDPLKIIT EDELTAQDIT ECNSNKENSE QPQFPVKSKK PSSKGKKKES CSKHASGTSF
HLPQPSFRMV DSGSQPEAPP LPAAYYRYIE KPPEDLDAEV EYDMDEEDLA WLDMVNEKRR
VDGHSLVSAD TFELLVDRLE KESYLESRSS GAQQSLIDED AFCCVCLDDE CHNSNVILFC
DICNLAVHQE CYGVPYIPEG QWLCRCCLQS PSRPVDCVLC PNKGGAFKQT SDGHWAHVVC
AIWIPEVCFA NTVFLEPIEG IDNIPAARWK LTCYICKQKG LGAAIQCHKV NCYTAFHVTC
AQRAGLFMKI EPMRETSLNG TIFTVRKTAY CEVHSPPGAA TARRKGDSPG SLSEVGDEEG
LKEGCGEEEE KEEVEEEEED EGQGGVGGPL KGVSKKNKMT LKQRIKKEPE EVGRDTPSTV
PMVTVPQIPS YRLNKICSGL SFQRKTQFMQ RLHNYWLLKR QARNGVPLIR RLHSHLQSQR
NAEQREQDEK TNAVKEELKY WQKLRHDLER ARLLIELIRK REKLKREQVK VQQAAMELEL
MPFNVLLRTT LDLLQEKDPA HIFAEPVNLN YLEFISKPMD FSTMRRKLES HLYGTLEEFE
EDFNLIVTNC MKYNAKDTIF HRAAVRLRDL GGAILRHARR QAENIGYDPE RGTHLPESPK
LEDFYRFSWE DVDNILIPEN RAHLSPEVQL KELLEKLDLV SAMRSSGART RRVRLLRREI
NALRQKLAQP PPPQLASLNK TVSNGELPAG PRGDVAVLEQ APQEEPEDDG DRDDSKMPPP
PTLEPTGPAP SLSEQESPPD PPTLKPINDS KPPSRFPKPR KVEEDELLEK SPLQLGNEPL
QHLLSDNGIN RVSLMTPDTS PAGAPLSGVG RRTSVLFKKA KNGVKLQRSP DRALENGEDH
GAVGSPASPT SIEDEQHSRK RPRSRSCSES EGERSPQQGE ETGVTNGFGK HTESGSDSEC
SLGLSGGLAF EACSGLTPPK RSRGKPALSR VPFLEGVNGD SDYNGSGRSL LMPFEDRGDL
EPLELVWAKC RGYPSYPALI IDPKMPREGL LHNGVPIPVP PLDVLKLGEQ KQAEAGEKLF
LVLFFDNKRT WQWLPRDKVL PLGVEDTVDK LKMLEGRKTS IRKSVQVAYD RAMIHLSRVR
GPHSFVTSSY LACMYFSFLY WVAGKSADSC LQSLQKFSA
//
