ID A0A4V6I9C9_9BURK Unreviewed; 370 AA.
AC A0A4V6I9C9;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Mechanosensitive ion channel family protein {ECO:0000313|EMBL:TMS58828.1};
GN ORFNames=MW7_009010 {ECO:0000313|EMBL:TMS58828.1};
OS Burkholderiaceae bacterium PBA.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae.
OX NCBI_TaxID=795666 {ECO:0000313|EMBL:TMS58828.1, ECO:0000313|Proteomes:UP000004277};
RN [1] {ECO:0000313|EMBL:TMS58828.1, ECO:0000313|Proteomes:UP000004277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PBA {ECO:0000313|EMBL:TMS58828.1,
RC ECO:0000313|Proteomes:UP000004277};
RA Gan H.M.;
RT "Revised genome assembly of Burkholderiaceae (previously Ralstonia) sp.
RT PBA.";
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TMS58828.1}.
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DR EMBL; AKCV02000015; TMS58828.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4V6I9C9; -.
DR STRING; 795666.MW7_1958; -.
DR OrthoDB; 9775207at2; -.
DR Proteomes; UP000004277; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049142; MS_channel_1st.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30566:SF25; INNER MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR30566; YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; 1.
DR Pfam; PF21088; MS_channel_1st; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004277};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 13..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 136..177
FT /note="Mechanosensitive ion channel transmembrane helices
FT 2/3"
FT /evidence="ECO:0000259|Pfam:PF21088"
FT DOMAIN 178..245
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 252..336
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 370 AA; 41162 MW; 951C4DB73FF13542 CRC64;
MTWFETEFLG NSVLRWLSAG AAGLAIYLVL RIVFRFAGER SARAARQTAT NFDDLLGQML
ASTRQWALLA GALLLASRML DLPERWHTRI DYLWFLVVGL QIGLWLNQGI SYWVKHRLDQ
RQGNTGNPVI TTIISWILRL FVWTLVVLAV LANMGVNITA MVASLGIGGV AVALAVQNIL
GDLFASAAIG LDKPFEIGDF IVFGDIAGSV EHVGLKTTRI RALSGEQIVC SNTQLLTNTI
HNYKRMAERR IQFAFGIAQA TPAAQLEQIP RIVREAIEAA GNTRFDRAHF KEFGESALNF
EVVYFVTSPD YNLYMDVQQS VNLALKKRLD TLGIDFALPA RRLAAPGIEN LLREQADRYE
GRETTLGHAR
//
