ID A0A4V6M4Y3_CAEEL Unreviewed; 1235 AA.
AC A0A4V6M4Y3;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=TropoNin T {ECO:0000313|EMBL:VTW47481.1};
GN Name=tnt-3 {ECO:0000313|EMBL:VTW47481.1,
GN ECO:0000313|WormBase:C14F5.3e};
GN ORFNames=C14F5.3 {ECO:0000313|WormBase:C14F5.3e}, CELE_C14F5.3
GN {ECO:0000313|EMBL:VTW47481.1};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:VTW47481.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:VTW47481.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:VTW47481.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the troponin T family.
CC {ECO:0000256|ARBA:ARBA00008330}.
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DR EMBL; BX284606; VTW47481.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4V6M4Y3; -.
DR EnsemblMetazoa; C14F5.3e.1; C14F5.3e.1; WBGene00006588.
DR AGR; WB:WBGene00006588; -.
DR WormBase; C14F5.3e; CE53396; WBGene00006588; tnt-3.
DR InParanoid; A0A4V6M4Y3; -.
DR OrthoDB; 2968211at2759; -.
DR Reactome; R-CEL-390522; Striated Muscle Contraction.
DR Proteomes; UP000001940; Chromosome X.
DR ExpressionAtlas; A0A4V6M4Y3; baseline and differential.
DR GO; GO:0005861; C:troponin complex; IBA:GO_Central.
DR GO; GO:0005523; F:tropomyosin binding; IBA:GO_Central.
DR GO; GO:0006936; P:muscle contraction; IBA:GO_Central.
DR GO; GO:0006937; P:regulation of muscle contraction; IEA:InterPro.
DR GO; GO:0045214; P:sarcomere organization; IBA:GO_Central.
DR Gene3D; 1.20.5.350; -; 1.
DR InterPro; IPR027707; TNNT.
DR InterPro; IPR001978; Troponin.
DR InterPro; IPR038077; Troponin_sf.
DR PANTHER; PTHR11521; TROPONIN T; 1.
DR PANTHER; PTHR11521:SF24; TROPONIN T; 1.
DR Pfam; PF00992; Troponin; 1.
DR SUPFAM; SSF90250; Troponin coil-coiled subunits; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Proteomics identification {ECO:0007829|EPD:A0A4V6M4Y3,
KW ECO:0007829|PeptideAtlas:A0A4V6M4Y3};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT REGION 1..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 242..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 633..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 864..1025
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1089..1116
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..146
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 682..698
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 880..1001
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1235 AA; 141287 MW; 99424B19A7471E8E CRC64;
MRSSFTSSYS SSSTLNPSSA SSPLSFSSSS SQLGFRRSSA TGSHGLASRS GTDYGNPFQR
DSSTRDTLPA RLYPTRSSSL AGRPEAPISS RVTRDEQTVG LLERYGNGAR KTSVGESSTS
QYFKQRRQQQ SEPDSGPSSS AHGQRRQSLE AGPYGPSSPF SPFGRDQPSS SSASHFGRDG
GRQTMADPQD LNQNEYMQRL LAAHNRVDDL LRSRGLGGED ERKYLRAWEE IPIIREERYR
RVRTPSSSSD SGLSTDNDSD RSNAEAAPPA DPPSVDSTDF FSFEREEEDI QIVHNYIVTA
KVKAYYSEKL KNVEFSLDKK AKSEKASKLL NAPSTPYMSH LSVTKAKDFK ATNKNKKKNS
ICDTRATFPS ETKETISITL PAAPTPKVLM NARQDLKKTP EKIIPKLKEA MSKCTKTLRA
VANKESIEKM LDEPPSSLSV SASFSVGDMR ELKKPHLPKR RKTYDDNVKV QQKNVLASLK
RKKMNVIPSA AEISIQHCSF YNQLAKDNFA EKNVRLNLRM TERAPKNCST QIVLPSPPRV
IYVRKDINAF YTKPPPRRTK TQEIPKPKIG RLNRAFTVEL EEKEKEIRKV NRLKIPEYFL
QSNAEMLEDI MGIKNGLKRV PIIGGFLVQP KEKAPVQQQS SLRRAGAIRR KPTPIKEEPS
APYSDFCPPQ TPSSPLPRIR IVSPLEPDPP PIPRRRPPPA SSSRHLNLHG SLALSAKPRG
AAKNYESIQH QKTLAELSET DKLLIERFSS QMHIPRPKAI IRALSPFNAI RALKSQFKER
CSSPPARFIH RRAPRMRSPT PAREMKPVRL ASVVIVKKQL PRRHWLDFQV DLKRIDFDKH
RSRLKPKMRL MRWIPRWRRR GTDEEVEEVD EEEVEADYAP SETDTTRSDR PKTKSFTEDE
EGLTEGERAM AAAKRRHEEE QHAKLQDYEE RRRTEREKEE EELKKLKEKQ EKRKLEREQE
EKEMEERRRA ADDRRRQEEE ERKAKVDQDR RNREEEKNKK NQLSGFQTGG QGGRNFTVAK
KAAQNDKFGN IVQAKQEMGM TKEQQEDAKR AFLAAIRKEI PNASEVPQSE LKAKIKELHQ
RICKLETEKY DLEKRHERQE YDMKELNERQ RQVTRNSALK KGIDPAEVGN TRYPPKQLIA
SKFERQRVQT FSDRRALFTN TKKLDTDAYF DWLNSFNYIA PQSLNIISAR DDIHAYLNSP
DRCPKYIEKE PTICTSQPVF TPRRLSIPAA FLKQG
//
