ID   A0A4W2BQE6_BOBOX        Unreviewed;       915 AA.
AC   A0A4W2BQE6;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=GTF2I repeat domain containing 1 {ECO:0000313|Ensembl:ENSBIXP00005028980.1};
GN   Name=GTF2IRD1 {ECO:0000313|Ensembl:ENSBIXP00005028980.1};
OS   Bos indicus x Bos taurus (Hybrid cattle).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=30522 {ECO:0000313|Ensembl:ENSBIXP00000001050.1, ECO:0000313|Proteomes:UP000314981};
RN   [1] {ECO:0000313|Proteomes:UP000314981, ECO:0000313|Proteomes:UP000429181}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Low W.Y., Tearle R., Bickhart D.M., Rosen B.D., Koren S., Rhie A.,
RA   Hiendleder S., Phillippy A.M., Smith T.P.L., Williams J.L.;
RT   "Haplotype-resolved cattle genomes.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSBIXP00000001050.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   Ensembl; ENSBIXT00000014866.1; ENSBIXP00000001050.1; ENSBIXG00000028999.1.
DR   Ensembl; ENSBIXT00005012192.1; ENSBIXP00005028980.1; ENSBIXG00005008846.1.
DR   GeneTree; ENSGT00940000159414; -.
DR   Proteomes; UP000314981; Chromosome 25.
DR   Proteomes; UP000429181; Chromosome 25.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 3.90.1460.10; GTF2I-like; 5.
DR   InterPro; IPR004212; GTF2I.
DR   InterPro; IPR036647; GTF2I-like_rpt_sf.
DR   InterPro; IPR016659; TF_II-I.
DR   PANTHER; PTHR46304; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR46304:SF1; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF02946; GTF2I; 5.
DR   PIRSF; PIRSF016441; TF_II-I; 1.
DR   SUPFAM; SSF117773; GTF2I-like repeat; 5.
DR   PROSITE; PS51139; GTF2I; 5.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000314981};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   REGION          95..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          231..251
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          278..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          468..561
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          892..915
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        95..109
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        541..561
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   915 AA;  101151 MW;  D430AEE49ED99A46 CRC64;
     MALLGKRCDI PANGCGPDRW TSAFTRKDEI ITSLVSALDS MCSALSKLNA EVACVAVHDE
     SAFVVGTEKG RMFLNARKEL QSDFLRFCRG APWKEPEAEH PKKVPRGEGG GRNVPRSALE
     HGSDVYLLRK MVEEVFDVLY SEALGRASVV PLPYERLLRE PGLLAVQGLP EGLAFRRPAE
     YDPKALMAIL EHSHRIRFKL KRPLEDGGRD SKALVELNGV SLLAKGARDC GLHGQTPKGP
     PQDLPPPATS SSVASFLYST ALPNHAVREL KQEAPACPLG PSDLGLGRPG PEPKAPAAQD
     FPDCCGQKPT GPGGPLIQNV HASKRILFSI VHDKSEKWDA FIKETEDINT LRECVQILFN
     SRYAEALGLD HMVPVPYRKI ACDPEAVEIV GIPDKIPFKR PCTYGVPKLK RILEERHSIH
     FVIKRMFDER IFTGNKFTKD PTKLEPASPP EDASTEVARA AVLDLAGTTR SDKSSLSEDC
     GPGTSGELGG LRPIKIEPED PDIIQVTVPD PSPASEEMTD SMPGHLPSED SGYGMEMLTD
     KGAGEDPRPE ERPVEDSHGD VIRPLRKQVE LLFNTRYAKA IGISEPVKVP YSKFLMYPEE
     LFVVGLPEGI SLRRPNCFGI AKLRKILEAS NSIQFVIKRP ELLTEGVKEP LSDSQERDSG
     DPLVDESLKR QGFQENYDAR LSRIDIANTL REQVQDLFNK KYGEALGIKY PVQVPYKRIK
     SNPGSVIIEG LPPGIPFRKP CTFGSQNLER ILAVADKIKF TVTRPFQGLI PKPDEDDANR
     LGEKVILREQ VKELFNEKYG EALGLNRPVL VPYKLIRDSP DAVEVTGLPD DIPFRNPNTY
     DIHRLEKILK AREHVRMVII NQLQPFAEIC NDAKVPAMAN VHGGLCRPER ATPGTSELLD
     LSAESGPHSE RLKEM
//