ID A0A4W2D1K0_BOBOX Unreviewed; 444 AA.
AC A0A4W2D1K0;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Peripherin {ECO:0000313|Ensembl:ENSBIXP00005015777.1};
GN Name=PRPH {ECO:0000313|Ensembl:ENSBIXP00000018050.1};
OS Bos indicus x Bos taurus (Hybrid cattle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=30522 {ECO:0000313|Ensembl:ENSBIXP00000018050.1, ECO:0000313|Proteomes:UP000314981};
RN [1] {ECO:0000313|Proteomes:UP000314981, ECO:0000313|Proteomes:UP000429181}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Low W.Y., Tearle R., Bickhart D.M., Rosen B.D., Koren S., Rhie A.,
RA Hiendleder S., Phillippy A.M., Smith T.P.L., Williams J.L.;
RT "Haplotype-resolved cattle genomes.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBIXP00000018050.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR Ensembl; ENSBIXT00000030859.1; ENSBIXP00000018050.1; ENSBIXG00000021944.1.
DR Ensembl; ENSBIXT00005047851.1; ENSBIXP00005015777.1; ENSBIXG00005003191.1.
DR GeneTree; ENSGT00940000160203; -.
DR Proteomes; UP000314981; Chromosome 5.
DR Proteomes; UP000429181; Chromosome 5.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR006821; Intermed_filament_DNA-bd.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR PANTHER; PTHR45652:SF14; PERIPHERIN; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF04732; Filament_head; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000314981}.
FT DOMAIN 96..406
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 86..248
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 293..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 444 AA; 50736 MW; 16B9651085160094 CRC64;
MSHPSGLRSS VSSTSYRRTF GPPPSLSPGA FSYSSSSRFS SSRLLGSASP GSSVRLGSFR
GPRAGTGALL RLPSERLDFS MAEALNQEFL ATRSNEKQEL QELNDRFANF IEKVRFLEQQ
NAALRGELNQ ARGQEPARAD QLCQQELREL RRELELLGRE RDRVQVERDG LAEDLAALKQ
RLEEETRKRE DAEHNLVLFR KDVDDATLSR LELERKIESL MDEIEFLKKL HEEELRDLQL
SVESQQVQHV EVEATVKPEL TAALRDIRAQ YESIAAKNLQ EAEEWYKSKY ADLSDAANRN
HEALRQAKQE MNESRRQIQS LTCEVDGLRG TNEALLRQLR ELEEQFALEA GGYQAGAARL
EEELRQLKEE MARHLREYQE LLNVKMALDI EIATYRKLLE GEESRISVPV HSFASLSIKT
TDYRNDVGQK ANWSNFLIRV QNGS
//
