ID   A0A4W2DR87_BOBOX        Unreviewed;       934 AA.
AC   A0A4W2DR87;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=General transcription factor IIi {ECO:0008006|Google:ProtNLM};
GN   Name=GTF2I {ECO:0000313|Ensembl:ENSBIXP00000027004.1};
OS   Bos indicus x Bos taurus (Hybrid cattle).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=30522 {ECO:0000313|Ensembl:ENSBIXP00000027004.1, ECO:0000313|Proteomes:UP000314981};
RN   [1] {ECO:0000313|Ensembl:ENSBIXP00000027004.1, ECO:0000313|Proteomes:UP000314981}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Low W.Y., Tearle R., Bickhart D.M., Rosen B.D., Koren S., Rhie A.,
RA   Hiendleder S., Phillippy A.M., Smith T.P.L., Williams J.L.;
RT   "Haplotype-resolved cattle genomes.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSBIXP00000027004.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A4W2DR87; -.
DR   Ensembl; ENSBIXT00000014816.1; ENSBIXP00000027004.1; ENSBIXG00000028937.1.
DR   Proteomes; UP000314981; Chromosome 25.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 3.90.1460.10; GTF2I-like; 6.
DR   InterPro; IPR004212; GTF2I.
DR   InterPro; IPR036647; GTF2I-like_rpt_sf.
DR   InterPro; IPR016659; TF_II-I.
DR   PANTHER; PTHR46304:SF2; GENERAL TRANSCRIPTION FACTOR II-I; 1.
DR   PANTHER; PTHR46304; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF02946; GTF2I; 6.
DR   PIRSF; PIRSF016441; TF_II-I; 1.
DR   SUPFAM; SSF117773; GTF2I-like repeat; 6.
DR   PROSITE; PS51139; GTF2I; 6.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000314981};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   REGION          208..231
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          250..324
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          642..661
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          667..694
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          796..817
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        668..693
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   934 AA;  105365 MW;  0B75622B66B6F332 CRC64;
     MAQVAVSTLP VEDEESSESR MVVTFLMSAL ESMCKELAKS KAEVACIAVY ETDVFVVGTE
     RGRAFVNTRK DFQKDFVKYC VEEEEKAAEM HKMKSTAQAN RMSVDAVEIE TLRKTVEDYF
     CFCYGKALGK STVVPVPYEK MLRDQSAVVV QGLPEGVAFK HPENYDLATL KWILENKAGI
     SFIIKRPFLE PKKHLGGRVM VTDAERSMIS PSGSCGPVKV KTEPSEDSGI SLEMAAVTVK
     EESEDPDYYQ YNIQGSHHSS EGNEGTEMEV PAEDSTQHVP SETSEDPEVE VTIEDDDYPP
     PAKRPKSSEP PQPPVTEPAN AGKRKVREFN FEKWNARITD LRKQVEELFE RKYAQAIKAK
     GPVTIPYPLF QSHVEDLYVE GLPEGIPFRR PSTYGIPRLE RILLAKERIR FVIKKHELLN
     STREDLQLDK PASGVKEEWY ARITKLRKMV DQLFCKKFAE ALGSTEAKAV PYQKFEAHPN
     DLYVEGLPEN IPFRSPSWYG IPRLEKIIQV GNRIKFVIKR PELLTHSTTE VTQPRTNTPV
     KEDWNVRITK LRKQVEEIFN LKFAQALGLT EAVKVPYPVF ESNPEFLYVE GLPEGIPFRS
     PTWFGIPRLE RIVRGSNKIK FVVKKPELVI SYLPPGMASK INTKALQSPK RPRSPGSNSK
     VPEIEVTVEG PNNSNPQTSA VRTPTQTNGS NVPFKPRGRE FSFEAWNAKI TDLKQKVENL
     FNEKCGEALG LKQAVKVPFA LFESFPEDFY VEGLPEGVPF RRPSTFGIPR LEKILRNKAK
     IKFIIKKPEM FETAIKESTS SSKSPPRKIN SSPSVNTTAS GVEDLNIIQV TIPDDDNERL
     SKVEKARQLR EQVNDLFSRK FGEAIGMGFP VKVPYRKITI NPGCVVVDGM PPGVSFKAPS
     YLEISSMRRI LDSAEFIKFT VIRPFPGLVI NNPF
//