ID A0A4W3I4G0_CALMI Unreviewed; 2415 AA.
AC A0A4W3I4G0;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Ankyrin repeat domain 26 {ECO:0000313|Ensembl:ENSCMIP00000024824.1};
GN Name=ankrd26 {ECO:0000313|Ensembl:ENSCMIP00000024824.1};
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|Ensembl:ENSCMIP00000024824.1, ECO:0000313|Proteomes:UP000314986};
RN [1] {ECO:0000313|Proteomes:UP000314986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17185593; DOI=10.1126/science.1130708;
RA Venkatesh B., Kirkness E.F., Loh Y.H., Halpern A.L., Lee A.P., Johnson J.,
RA Dandona N., Viswanathan L.D., Tay A., Venter J.C., Strausberg R.L.,
RA Brenner S.;
RT "Ancient noncoding elements conserved in the human genome.";
RL Science 314:1892-1892(2006).
RN [2] {ECO:0000313|Proteomes:UP000314986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17407382;
RA Venkatesh B., Kirkness E.F., Loh Y.H., Halpern A.L., Lee A.P., Johnson J.,
RA Dandona N., Viswanathan L.D., Tay A., Venter J.C., Strausberg R.L.,
RA Brenner S.;
RT "Survey sequencing and comparative analysis of the elephant shark
RT (Callorhinchus milii) genome.";
RL PLoS Biol. 5:E101-E101(2007).
RN [3] {ECO:0000313|Proteomes:UP000314986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
RN [4] {ECO:0000313|Ensembl:ENSCMIP00000024824.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSCMIT00000025235.1; ENSCMIP00000024824.1; ENSCMIG00000010941.1.
DR GeneTree; ENSGT00940000163982; -.
DR Proteomes; UP000314986; Unassembled WGS sequence.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR039497; CC144C-like_CC_dom.
DR InterPro; IPR021885; DUF3496.
DR PANTHER; PTHR24147; ANKYRIN REPEAT DOMAIN 36-RELATED; 1.
DR PANTHER; PTHR24147:SF53; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 26 ISOFORM X1; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF14915; CCDC144C; 1.
DR Pfam; PF12001; DUF3496; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 7.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 4.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000314986}.
FT REPEAT 66..98
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 132..164
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 165..197
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 198..230
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 1469..1772
FT /note="CCDC144C-like coiled-coil"
FT /evidence="ECO:0000259|Pfam:PF14915"
FT DOMAIN 2206..2292
FT /note="DUF3496"
FT /evidence="ECO:0000259|Pfam:PF12001"
FT REGION 297..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 517..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 669..721
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 765..871
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 895..927
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1103..1124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1035..1067
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1287..1419
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1476..1574
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1607..1711
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1741..1908
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1989..2051
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2075..2226
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2255..2282
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 324..338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..412
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..459
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 518..532
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 540..564
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..599
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 621..635
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..690
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 705..721
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 783..798
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 816..840
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 910..927
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2415 AA; 275372 MW; 6933157309B98C57 CRC64;
MKKIFSFAKR KRGLSQSTSD TASVVSAGYE LKDKDLGKLH KAASAGDVAK LRQLIKKHDI
NQLDKENRTP LHLACAGGHA ESVAFLVENK SKLNICDNDN RSPLMKAVQC QQERCALILL
DHDADPNLVD INDNTAMHLA ALIPNISVAI HLLEHEARID IRNKEGFTPL LLAVNENHQE
MVEFLLKEGA NINAKDLAGR TSLMLAASTG QISMVKLLLQ YDADITMKED KGWTADDYAV
MNGHHACSHL IIEHGTKKKL HQSPPYYGTS KVKGVSMFSS PDRAAEAAFA LGGPATDREA
FQQSPEQKSR ASESEKVEYD ASQGESVSRA SNVASDSWPS SDEEEELDFS PKKLQKPSLA
KLVNASQQSK KKINEKANSS KVQQMAISHP LKSNVDSEED SEEDSEDEEE IIENYGLQTH
PSPHAKALVV SPQAAVPSPS SFVEPPQSIS TPSKGFKQDR VQDGSSDEEE EVEEQHVGKF
RDTTKEPVIQ NTISNIIQQE KEASHQKVQR DLMSELGLEE IDGEEDIESP WDSESITESL
KKKSSASSSA KDQIKMNSIL ENQDDESPEG IAAAQMPSPK IAVDKHKSEF GKGDAGVIEE
TDWDSEETNL PLGKITPEVH SVAKTTIQAS GPQETEPKMP LSEEEDDDEE KCDWERKKDK
HIFETTRVND TVSNECPPSA NKTGVADILL SQQKENEIDL NEDPDFDSSE KSAEVVETNE
KSGMLLEERY EKVWVEKEKR EIASHLKSLT AELRQSFEEI RQNKVSAVGD AEDNSGGDSS
SESDEILFHK KNEDTALEQP SEEYDVCDNE GRILQPIPEQ QESITEDFSS KATDVGNKPQ
ISLEPQKLPE LKTKEDSDDM PPFPPAGNAV SKELQWETVK EDLVKETEIY FPKEGGTDIA
GYVTDLDSDG GNDGSLQVHS GSNKNICSDD ENPSPLENTH LLNKIKLVGF TPTKGEGCEL
QDNIMARGLL PQNVKTPEHE DFPHPDAKTP ETLIDDLEYS PRKPPVIASK PYSDEELEED
VQRFKNEVGM LKVVFLALEK KKAQLQKEVE EEKRKNLQNR ERNQLDEMKL TELAGKYEGS
QHLQVKQVAE KIIHEKVNQR TEPKLLKEQV GKDGDRPKQQ NTSLIFRINE ERQRESFLKE
RIKKQNIFKG IELGSDEDDY ENRQHNQWPK QIGQELKRKD RRLALQQTSC VNGDSLSAFY
DSTPSEMSQD EAGVLKTATK KASRVVTVSD DLDDLTQSSD STADSSESPA SVYRNAPLLI
AQLGAEKLDS VSLLKIQNLM YEYERSVERE KSRYSLLSEK VKQLENERKE HYQTLEETRE
MKSKLEHQKV EWETDLNSLR FRIKQEEEKR KNAEMLYEKS REQVQKKEAQ YCKEIEAKQE
LEQTVRNLEM ERRTLISNLK QLDEEQNDLQ RVLSQERSAR VVHEGIFNNH LRKQREIDEE
NKKSVSKNTE ALIHFSETNE REKDLMQQNC SLQDEVSVLK LELDRVRARN QEEQGKYMEE
NEALKERLEY LKKDLKDNEE ALTQTALQCN GQLNALKTET AMLASQLERE KQNREKLETD
MEIMHSRLNS ALQEIELSQT AKGDGEKTFQ RERDEWLRLD EKRNHEISNL RETTNSLSQQ
LSKAEAKANN LDNESHRATL SLTEKNLILE SVQRDLNQSL ARTKELEHAL HLEKEQMSKY
TVRQESMQER LAQTQSDNML LRQQLEDAHN KGIKKEQAVS DVQERFSDIF SKLRGDSERQ
INLIEERNKE LIIRNNEQKE HIYKFENEKT ERESILRQHQ QELADALKKL SMSEASLEVT
TRYRNELEEE KTRMQKQLDK LKSKLQNTEE KHVHSERRIQ ELQNALDEKE HQVIASSQKM
QELLTVSSQS KEGAKQLEEH VQRLEIENAK LEALVKQKTS RSEMLQKELQ ETASSPGYTT
ERIVGHYEDT TVRGRLEDLV TSLQGVKVNL EEQLNQEVQK QVVLSQTAKD SHHLWEEELK
SRSKLGLRLS KLDREKDELA SQIESEKKKV KKIAEGKRSV ETRLDQEMKR NAELQKELSR
MRTLLKGTKK KLKEYENGGF VSQLSSIRGE LDHRHSETEV TINKLKSKVD ELSQQLEVEY
VKCRRLESAS QEQLEQVASM RSLQRNHDRL EKSKQHLEDE VARLKRQVET NVMDHSHMEQ
YKREIEEHAR KEIKQKLEEV NLFLQTQQAS QEALEQLRAT NEGTVRNQLE QRIRDLESEL
TRVRSSQQDS LNLRESAQSE VERYKELYTE ELKSRKSLAA KLDRANERLS EANTKLLNER
QRSKSLIASS IMNGSLTATP ALDMGQLQSA MANIGNNMGT FNRNFSIGGN FPSPVVDGMS
STNRVESYLT KMQNALEKNI SKELHEATAD LDGIPTRVSP QGSAASSLKS INQDQDPVTR
ATQQYLEVLK KNYML
//
