ID A0A4W3KB69_CALMI Unreviewed; 290 AA.
AC A0A4W3KB69;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Inflammation and lipid regulator with UBA-like and NBR1-like domains {ECO:0000313|Ensembl:ENSCMIP00000042190.1};
GN Name=ilrun {ECO:0000313|Ensembl:ENSCMIP00000042190.1};
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|Ensembl:ENSCMIP00000042190.1, ECO:0000313|Proteomes:UP000314986};
RN [1] {ECO:0000313|Proteomes:UP000314986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17185593; DOI=10.1126/science.1130708;
RA Venkatesh B., Kirkness E.F., Loh Y.H., Halpern A.L., Lee A.P., Johnson J.,
RA Dandona N., Viswanathan L.D., Tay A., Venter J.C., Strausberg R.L.,
RA Brenner S.;
RT "Ancient noncoding elements conserved in the human genome.";
RL Science 314:1892-1892(2006).
RN [2] {ECO:0000313|Proteomes:UP000314986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17407382;
RA Venkatesh B., Kirkness E.F., Loh Y.H., Halpern A.L., Lee A.P., Johnson J.,
RA Dandona N., Viswanathan L.D., Tay A., Venter J.C., Strausberg R.L.,
RA Brenner S.;
RT "Survey sequencing and comparative analysis of the elephant shark
RT (Callorhinchus milii) genome.";
RL PLoS Biol. 5:E101-E101(2007).
RN [3] {ECO:0000313|Proteomes:UP000314986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
RN [4] {ECO:0000313|Ensembl:ENSCMIP00000042190.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007892334.1; XM_007894143.1.
DR AlphaFoldDB; A0A4W3KB69; -.
DR STRING; 7868.ENSCMIP00000042190; -.
DR Ensembl; ENSCMIT00000042796.1; ENSCMIP00000042190.1; ENSCMIG00000017534.1.
DR GeneTree; ENSGT00490000043415; -.
DR InParanoid; A0A4W3KB69; -.
DR OMA; ESKWRMS; -.
DR OrthoDB; 145583at2759; -.
DR Proteomes; UP000314986; Unassembled WGS sequence.
DR CDD; cd14947; NBR1_like; 1.
DR CDD; cd14349; UBA_CF106; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR039517; C6orf106_UBA-like.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR032350; N_BRCA1_central.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR20930; OVARIAN CARCINOMA ANTIGEN CA125-RELATED; 1.
DR PANTHER; PTHR20930:SF0; PROTEIN ILRUN; 1.
DR Pfam; PF16158; N_BRCA1_IG; 1.
DR Pfam; PF14555; UBA_4; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000314986}.
FT DOMAIN 81..178
FT /note="Next to BRCA1 central"
FT /evidence="ECO:0000259|Pfam:PF16158"
FT REGION 204..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..220
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..269
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 290 AA; 32015 MW; 00E394FAA7A1D265 CRC64;
MDVDMELDQD LMQKFSCLGT TDKDVLISEF QRLLGFQLNP AGCAFFLDMT NWNLQAAIGA
YYDFESPNIN APSMSFVEDV TIGEGESVPP DTQFTKTWRI QNTGAEQWPP GVSLKYVGGD
QFGHVNMVMV RSLEPQEVTD VSVQMRSPST SGMFQGQWRM CTATGLYFGD VIWVILSVEV
GGLLGVTQQL SSFETEFSSQ PCRKIEGNFN PFASPQKNRQ SEDSIVKDPG GRGTNPISKN
AWSPSQDQNE QEQNGLSQKS VNISPNSHSS NLSVVTYSQG FHGPYPFGQS
//
