ID A0A4W4DXS9_ELEEL Unreviewed; 690 AA.
AC A0A4W4DXS9;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=BICD cargo adaptor 2 {ECO:0000313|Ensembl:ENSEEEP00000003685.1};
GN Name=BICD2 {ECO:0000313|Ensembl:ENSEEEP00000003685.1};
OS Electrophorus electricus (Electric eel) (Gymnotus electricus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Gymnotiformes;
OC Gymnotoidei; Gymnotidae; Electrophorus.
OX NCBI_TaxID=8005 {ECO:0000313|Ensembl:ENSEEEP00000003685.1, ECO:0000313|Proteomes:UP000314983};
RN [1] {ECO:0000313|Proteomes:UP000314983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24970089;
RA Gallant J.R., Traeger L.L., Volkening J.D., Moffett H., Chen P.H.,
RA Novina C.D., Phillips G.N.Jr., Anand R., Wells G.B., Pinch M., Guth R.,
RA Unguez G.A., Albert J.S., Zakon H.H., Samanta M.P., Sussman M.R.;
RT "Nonhuman genetics. Genomic basis for the convergent evolution of electric
RT organs.";
RL Science 344:1522-1525(2014).
RN [2] {ECO:0000313|Proteomes:UP000314983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28695212;
RA Traeger L.L., Sabat G., Barrett-Wilt G.A., Wells G.B., Sussman M.R.;
RT "A tail of two voltages: Proteomic comparison of the three electric organs
RT of the electric eel.";
RL Sci. Adv. 3:e1700523-e1700523(2017).
RN [3] {ECO:0000313|Ensembl:ENSEEEP00000003685.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BicD family.
CC {ECO:0000256|ARBA:ARBA00010061}.
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DR Ensembl; ENSEEET00000003737.1; ENSEEEP00000003685.1; ENSEEEG00000002007.1.
DR GeneTree; ENSGT00940000154471; -.
DR Proteomes; UP000314983; Unassembled WGS sequence.
DR GO; GO:0008093; F:cytoskeletal anchor activity; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR Gene3D; 6.10.250.2470; -; 1.
DR InterPro; IPR018477; BICD.
DR PANTHER; PTHR31233; BICAUDAL D FAMILY MEMBER; 1.
DR PANTHER; PTHR31233:SF7; PROTEIN BICAUDAL D HOMOLOG 2; 1.
DR Pfam; PF09730; BicD; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000314983}.
FT REGION 280..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 658..690
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 41..75
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 140..254
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 333..533
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 564..640
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 663..690
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 690 AA; 78806 MW; EC3BA6D32080AA4F CRC64;
MSVEGMRVTG AGPEGMRAEL ERLSRELSET TREKIQAAEY GLAVLEEKQA LQQQYDELEL
EYETVRQEMD QLKEAFGQAH SNQRKVAADG ESREESLLQE SACKEAYYEQ RVQELQTEIR
QTRVALCNAQ AESERLSTVA QELRENSQMV ELQRSRLRDD IKEYKFREAR LLQDYSELEE
ENITLQKHVS VLKQGQVEFE GLKHEIRRLE EDTQFLNSQL EDAIRLKEIA ERQLGEALET
IKTEREQKAA LRKELSHYMS IGDSMYHNPL NISLDGLKFG EDAMTEPNND DPVNGYENSF
DKIPSGEDDN RVSTPKKSAR LQPAPSLVDD LLSELNISEI QKLKQQLVQV EREKVSLVST
LQDSQKQLEQ ANGALSEEHE KVSRLTENLN AIRKLQASKE RRSALDEEKE RDSREDGDYY
EVDINGPEIL ECKYKVVVSE AAQLKEELKT VRMEYSSCQS QYEEERARLE GQVTALVSKL
STLEHSSRVE REQLARVEKE LRRASEVAGE TQGSLSVAQD ELATFSEELA NLYXTPNRVM
LDYYREGKGG VAGRTAEVAL ANLKSKYENE KAMVTETMMK LRNELKALKE DAATFSSLRA
MFATRCDEYV TQLDEMQRQL AAAEDEKKTL NSLLRMAIQQ KLALTQRLED LEFDHEQCRR
GGANGRNKST SSRGRFPLSL SLSPASEKPT
//
