ID A0A4W4G5L2_ELEEL Unreviewed; 447 AA.
AC A0A4W4G5L2;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=NACC family member 2 {ECO:0000313|Ensembl:ENSEEEP00000032789.1};
GN Name=NACC2 {ECO:0000313|Ensembl:ENSEEEP00000032789.1};
OS Electrophorus electricus (Electric eel) (Gymnotus electricus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Gymnotiformes;
OC Gymnotoidei; Gymnotidae; Electrophorus.
OX NCBI_TaxID=8005 {ECO:0000313|Ensembl:ENSEEEP00000032789.1, ECO:0000313|Proteomes:UP000314983};
RN [1] {ECO:0000313|Proteomes:UP000314983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24970089;
RA Gallant J.R., Traeger L.L., Volkening J.D., Moffett H., Chen P.H.,
RA Novina C.D., Phillips G.N.Jr., Anand R., Wells G.B., Pinch M., Guth R.,
RA Unguez G.A., Albert J.S., Zakon H.H., Samanta M.P., Sussman M.R.;
RT "Nonhuman genetics. Genomic basis for the convergent evolution of electric
RT organs.";
RL Science 344:1522-1525(2014).
RN [2] {ECO:0000313|Proteomes:UP000314983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28695212;
RA Traeger L.L., Sabat G., Barrett-Wilt G.A., Wells G.B., Sussman M.R.;
RT "A tail of two voltages: Proteomic comparison of the three electric organs
RT of the electric eel.";
RL Sci. Adv. 3:e1700523-e1700523(2017).
RN [3] {ECO:0000313|Ensembl:ENSEEEP00000032789.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A4W4G5L2; -.
DR Ensembl; ENSEEET00000033180.1; ENSEEEP00000032789.1; ENSEEEG00000015617.1.
DR GeneTree; ENSGT00940000159244; -.
DR Proteomes; UP000314983; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.2590; BEN domain; 1.
DR InterPro; IPR018379; BEN_domain.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR46105; AGAP004733-PA; 1.
DR PANTHER; PTHR46105:SF2; NUCLEUS ACCUMBENS-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF10523; BEN; 1.
DR Pfam; PF00651; BTB; 1.
DR SMART; SM01025; BEN; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS51457; BEN; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Reference proteome {ECO:0000313|Proteomes:UP000314983};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 30..94
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DOMAIN 324..421
FT /note="BEN"
FT /evidence="ECO:0000259|PROSITE:PS51457"
FT REGION 131..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 218..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 447 AA; 48821 MW; ED099DB8634DE0D4 CRC64;
MSQMLHVEIP NFGSTVLGSL NEQRLMGQYC DVSILVKGQA FKAHRAVLAA SSLYFRDLFS
TSSKTQFELP SSVTPACFQQ ILSFCYTGKL TMAASEQLVV MYTAGYLQIQ HIVERGMDLM
FKANSPHCDS ATAAIDEPGS EPQSPSNLPA SVLGPPGWAP SLVAPARKIK LELGEQLLHL
QGGVKRTSSG DGGARAGRTS SLFYAGAVGL FPPNMQPYPI TPGERSSPGA SSLPTTDSPI
SYQNEDEEFE EESYDINEEA FSQIYGRVSD VTSVPLALES RPCMLLRRDL VALPASLISQ
IGYRCHPKLY TEGDPGEKLE LVAGTGVFMT RGQLMNCHLC AGIKHKVLLR RLLATFFDRN
TLANSCGTGI RSSTSDPSRK PLDSRVLNAV KLYCQNFAPN FKESEMNVIA ADMCTNARRV
RKRWLPKIKS MLPDGMEVTF LIQTGTI
//
