ID   A0A4W5JT24_9TELE        Unreviewed;       404 AA.
AC   A0A4W5JT24;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=Flotillin {ECO:0000256|RuleBase:RU366054};
OS   Hucho hucho (huchen).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Hucho.
OX   NCBI_TaxID=62062 {ECO:0000313|Ensembl:ENSHHUP00000002944.1, ECO:0000313|Proteomes:UP000314982};
RN   [1] {ECO:0000313|Proteomes:UP000314982}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Macqueen D.J., Gundappa M.K.;
RT   "Genome assembly of Danube salmon.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSHHUP00000002944.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBUNIT: Heterooligomeric complex. {ECO:0000256|RuleBase:RU366054}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU366054}.
CC       Endosome {ECO:0000256|RuleBase:RU366054}.
CC   -!- SIMILARITY: Belongs to the band 7/mec-2 family. Flotillin subfamily.
CC       {ECO:0000256|ARBA:ARBA00007161, ECO:0000256|RuleBase:RU366054}.
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DR   AlphaFoldDB; A0A4W5JT24; -.
DR   Ensembl; ENSHHUT00000003048.1; ENSHHUP00000002944.1; ENSHHUG00000001683.1.
DR   GeneTree; ENSGT00560000077232; -.
DR   Proteomes; UP000314982; Unassembled WGS sequence.
DR   GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd03399; SPFH_flotillin; 1.
DR   Gene3D; 3.30.479.30; Band 7 domain; 1.
DR   InterPro; IPR001107; Band_7.
DR   InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR   InterPro; IPR027705; Flotillin_fam.
DR   PANTHER; PTHR13806:SF32; FLOTILLIN; 1.
DR   PANTHER; PTHR13806; FLOTILLIN-RELATED; 1.
DR   Pfam; PF01145; Band_7; 1.
DR   SMART; SM00244; PHB; 1.
DR   SUPFAM; SSF117892; Band 7/SPFH domain; 1.
PE   3: Inferred from homology;
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU366054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000314982}.
FT   DOMAIN          74..256
FT                   /note="Band 7"
FT                   /evidence="ECO:0000259|SMART:SM00244"
SQ   SEQUENCE   404 AA;  45351 MW;  1C108294AEC5885E CRC64;
     IIYTCFGRSP PLMIAGGRVF VLPCIQQIQR ITLNTLTLNV KSDKVYTRHG VPISVTGIAQ
     VKIQGQNKEM LATACQMFMG KSEAEVSNIA LETLEGHQRA IIAHLTVEEI YQDRKKFSEQ
     VFKVASSDLV NMGIGVVSYT LKDVHDDQDY LNSLGKARTA QVQKDARIGE AQYKRDAVIR
     EAQAMQEKVS AQYLNEIEMA KAQRDYELKK ASYDYEVNTK KAESEMAYQL QVAKTKQRIE
     EETMQVKVVE RSQQIMLQEQ EITRKEMELE AKVKKPAEAE RYRLERLAEA ERYCVLIYSV
     SILSAKGRAE AEQMAKKAEA FKQYGEGAMV DMLLEKLPLI AEEISRPLSM AQKVTMVSSG
     GGEVGAAKLT GEVLDIMTRL PAAVEKLTGI NISQVCRMGQ RCML
//