ID   A0A4W5KYI6_9TELE        Unreviewed;       903 AA.
AC   A0A4W5KYI6;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Zgc:153039 {ECO:0000313|Ensembl:ENSHHUP00000016294.1};
OS   Hucho hucho (huchen).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Hucho.
OX   NCBI_TaxID=62062 {ECO:0000313|Ensembl:ENSHHUP00000016294.1, ECO:0000313|Proteomes:UP000314982};
RN   [1] {ECO:0000313|Proteomes:UP000314982}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Macqueen D.J., Gundappa M.K.;
RT   "Genome assembly of Danube salmon.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSHHUP00000016294.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the SLC12A transporter family.
CC       {ECO:0000256|ARBA:ARBA00010593}.
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DR   AlphaFoldDB; A0A4W5KYI6; -.
DR   Ensembl; ENSHHUT00000016868.1; ENSHHUP00000016294.1; ENSHHUG00000010132.1.
DR   GeneTree; ENSGT00940000164152; -.
DR   Proteomes; UP000314982; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR004841; AA-permease/SLC12A_dom.
DR   InterPro; IPR018491; SLC12_C.
DR   InterPro; IPR004842; SLC12A_fam.
DR   PANTHER; PTHR11827:SF96; SOLUTE CARRIER FAMILY 12 MEMBER 9; 1.
DR   PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR   Pfam; PF00324; AA_permease; 1.
DR   Pfam; PF03522; SLC12; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000314982};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        80..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        128..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        175..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        204..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        277..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        318..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        362..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        407..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        430..452
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        464..483
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        489..508
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          50..548
FT                   /note="Amino acid permease/ SLC12A"
FT                   /evidence="ECO:0000259|Pfam:PF00324"
FT   DOMAIN          560..648
FT                   /note="SLC12A transporter C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03522"
SQ   SEQUENCE   903 AA;  99628 MW;  C007D4304417577C CRC64;
     MSERTPLLHY RLSTSVIEQS GEHQPCLPRE AVEQSPALSR RPKKLSTFFG VVIPTLLSMF
     SVVVFLRIGF VVGQCGLYQA IAMFLVAYFI ISMTVLSVCA ISTNGALDAG GAYYMISRAL
     GPEFGGSLGV MFFLANVCSS ALYILGLVEA IVATFGLPED GVSPAGSLQV LPAGYWWSLL
     YATGILLLCL LVCLVGAEIY AKASFIIFLV VMLVLATIFI SFFAVRPRTI LLPAAPPIHN
     GTGPQPPTMA NFTGFKLNTL LGNLDADYAV DYTTGTMMSF ATVFAVMFNG CTGIMAGSNM
     SGDLKNPSYS IPRGTITAVI FTFIIYNLLS LMVACSCDRI LLQRDYSFLR DINVWNPLVT
     VGVYSSTMSA AMSNLIGASR ILYALARDDL FGTVLSIAKK TSRNGNPWVS VLLSWFLVQL
     VLFTGKLNTI ASIVTIFFLL VYAAVDLACL ALEWASAPNF RPTFRYFTWH TCVLGIVGCA
     VMMFLINSIY ASASIAFMLL LLLLIHYLSP TSSWGYISQA LIFHQVRKYL LMLDVRKDHV
     KFWRPQVLLM VSNPRSSVGL ITFINDIKKS GLYVLGHVQL GDLDTLPSDP LQCLYDSWLS
     LVDHLNIKAF VNLTLADSVR HGVQHLLFIS GLGGMRPNTL VLGFYDDCTP KDKLTDHNLA
     DATVPTQDPE DERPPYHFPA LRASIDGKEE GNGENGKVMG LQEYVAVIAD AMKMLKNVAL
     ARYFHQFDRA STISSSPGKG ALYVDVWPVN LLRPDSSSYV DTCSLFLLQL ACVLNMVRAW
     RHARLRLFLC VEEGRSLRGS EEKLGQLLKE LRIKANVYTV PWDQQVAFPS NATRLSDEYL
     SAVNRLILEQ ARPPPAVRFL YLPRPPADTR RYTAYLRQLD LLTKDLGPTL LIHGVTPVLT
     TDL
//