ID A0A4W5MB14_9TELE Unreviewed; 886 AA.
AC A0A4W5MB14;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Si:ch211-193k19.1 {ECO:0000313|Ensembl:ENSHHUP00000035602.1};
GN Name=KIAA0319L {ECO:0000313|Ensembl:ENSHHUP00000035602.1};
OS Hucho hucho (huchen).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Hucho.
OX NCBI_TaxID=62062 {ECO:0000313|Ensembl:ENSHHUP00000035602.1, ECO:0000313|Proteomes:UP000314982};
RN [1] {ECO:0000313|Proteomes:UP000314982}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Macqueen D.J., Gundappa M.K.;
RT "Genome assembly of Danube salmon.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSHHUP00000035602.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A4W5MB14; -.
DR Ensembl; ENSHHUT00000037036.1; ENSHHUP00000035602.1; ENSHHUG00000022365.1.
DR GeneTree; ENSGT00940000157613; -.
DR Proteomes; UP000314982; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR029865; KIAA0319-like.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR002859; PKD/REJ-like.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR46182:SF3; DYSLEXIA-ASSOCIATED PROTEIN KIAA0319-LIKE PROTEIN; 1.
DR PANTHER; PTHR46182; FI19480P1; 1.
DR Pfam; PF02010; REJ; 1.
DR SMART; SM00089; PKD; 4.
DR SUPFAM; SSF49299; PKD domain; 4.
DR PROSITE; PS50093; PKD; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000314982};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 733..758
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 335..395
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 769..886
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 772..789
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 809..833
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 886 AA; 96745 MW; 33FC96436AB5C7A9 CRC64;
ISWQRVSKDA EHPAPTVGNT SGVDLPQTSD KNHSQLTNGS GEAPSPSQQN STSEDTRDTA
SSNSSSVLPT TALTITTSPT QAGKAVDNFC FSVPPSVSTH ANPVVSMTVR ELAVSAGESV
EVTLPRNEVE LNAFVVPAPQ RGTNYAFDWL LRTHPKDYSG EMEGKHSKTL KLSKLTVGLY
EFEVTVDGDG AHGEGFVNVT VKPEPRINKL PVAVVSPKFQ EISLPTSSTV IDGSQSTDDD
KVVAWHWEEV KGPLREEKVS ADTQILTLTG LVPGNYTFSL TVTDSDGAQS STQATLSVSK
AMDYRPVANA GPNQVITLPR NAVTLHGNQS ADDHEPLAYE WSLSPESKGK VVEMQGVRTP
TLQLSAMQEG DYTFQLTVTD TAGQQDTAQV TVIVQPENNK PPVADPGPEK ELTLPVDRTT
LDGSKSTDDQ NISTYHWKQI KGPDGVKIEN ADGAVATVTG LQVGEYEFSL TVTDERNLAS
TETVTVIVRE ELDQPPVAHV QSRPAISLPL RTAALDGSHS TDDKGGVGYL WTRDDSSPAA
GDVLNNSDHQ AVLFLTNLVE GKYSFTLTVT DSKGQSSSDR GTVEVKPDVW QRDLVELVLE
VSVSQVSHRQ RDMLLRQVGV LLGVLDSDII VREVSAFNEH STRLVFLVSG GPGRPPLSGH
SVALGLRNKL RKQKNDFLIF KARRVDTVIC QLNCSSHGDC DSFTRTCVCH PFWMENFIKA
HLWDQESNCE WSVLYVTIAS FMIVVVIATV VWGMVCCYRR RRGKIRHKSK SRYKMLNGEE
QDSLELHPPR AGRMKPAPAP SSSALMHSDS DLDSDDGQGG VPWTDRERGH LLRPQNGTLR
NGQGPPRKCT PLTSRRKKRE TASQDDPVPF RQELYSFPMS CEPHGN
//
