ID A0A4W5QH70_9TELE Unreviewed; 733 AA.
AC A0A4W5QH70;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Phosphatidylinositol binding clathrin assembly protein b {ECO:0000313|Ensembl:ENSHHUP00000075422.1};
OS Hucho hucho (huchen).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Hucho.
OX NCBI_TaxID=62062 {ECO:0000313|Ensembl:ENSHHUP00000075422.1, ECO:0000313|Proteomes:UP000314982};
RN [1] {ECO:0000313|Proteomes:UP000314982}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Macqueen D.J., Gundappa M.K.;
RT "Genome assembly of Danube salmon.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSHHUP00000075422.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PICALM/SNAP91 family.
CC {ECO:0000256|ARBA:ARBA00008011}.
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DR AlphaFoldDB; A0A4W5QH70; -.
DR STRING; 62062.ENSHHUP00000075422; -.
DR Ensembl; ENSHHUT00000077896.1; ENSHHUP00000075422.1; ENSHHUG00000044104.1.
DR GeneTree; ENSGT00950000183068; -.
DR Proteomes; UP000314982; Unassembled WGS sequence.
DR GO; GO:0030136; C:clathrin-coated vesicle; IEA:InterPro.
DR GO; GO:0005545; F:1-phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0048268; P:clathrin coat assembly; IEA:InterPro.
DR GO; GO:0072583; P:clathrin-dependent endocytosis; IEA:InterPro.
DR CDD; cd16985; ANTH_N_AP180; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 1.20.58.150; ANTH domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR014712; ANTH_dom_sf.
DR InterPro; IPR045192; AP180-like.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR PANTHER; PTHR22951; CLATHRIN ASSEMBLY PROTEIN; 1.
DR PANTHER; PTHR22951:SF16; PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN; 1.
DR Pfam; PF07651; ANTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000314982}.
FT DOMAIN 14..145
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 619..640
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 685..733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 321..348
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 623..640
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..719
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 733 AA; 79524 MW; 4848DFF04CD0DCC4 CRC64;
MSGQSITDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIHCTN EMNVNIPQLA
DSLFERTTST SWVVVFKSLI ATHHLMVYGN ERFVQYLASR NTLFNLSNFL DKSGLQGYDM
STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GVDGVMRTMN TEKLLKTIPI IQSQMDALLD
FNVNANELTN GVINAGFMLL FKDSIRLFAA YNEGIINLLE KYFDMKKTQC KEGLDIYKKF
LTRMTRISEF LKVAEQVGID RGDIPDLSQA PSSLLEALEQ HLASLEGKKV KDSTAASRAS
TLSNAVSSLA STGMSFTKVD EREKQAALEE EQARLKALKE QRLKELSKMP SFATTDTSPV
STTGGTISTA PAIDLFSTPS CSNGALKMES DLFDIQQTFN PSMQASSTGL PVATAWADPF
TSAEAGDDSM PNLNPFLSKV VVDAAAHLPV VSSDGVSYSS RTSGHEMFGD RYNPFTDTNS
SVSSNYKRTV RIEHSISDSF CGGPVSMAQH LPHQAPYPTE PSTVAGLFRG YSTASQAPPP
GALQVDFESV FGAKATGVNN IDSDDILKPT MVGSNQALCS INQLSDKLVG DDLDSSLANL
VGNLGIGNGT TKNDIHWSQP GEKRLTGGSN WQPKAAPNTT WNTVSMTPPV MAYPATTPTG
MVGGYGMPPQ QLGSMGMMNQ PNMMYNQPIM RPPNPFGSVS SAQPSAASSP SSQSPLRAPG
QDPFAQLSLK DFL
//
