ID   A0A4W5RU04_9TELE        Unreviewed;       403 AA.
AC   A0A4W5RU04;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=NPHS2 stomatin family member, podocin {ECO:0000313|Ensembl:ENSHHUP00000088149.1};
OS   Hucho hucho (huchen).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Hucho.
OX   NCBI_TaxID=62062 {ECO:0000313|Ensembl:ENSHHUP00000088149.1, ECO:0000313|Proteomes:UP000314982};
RN   [1] {ECO:0000313|Proteomes:UP000314982}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Macqueen D.J., Gundappa M.K.;
RT   "Genome assembly of Danube salmon.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSHHUP00000088149.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the band 7/mec-2 family.
CC       {ECO:0000256|ARBA:ARBA00008164}.
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DR   AlphaFoldDB; A0A4W5RU04; -.
DR   Ensembl; ENSHHUT00000090892.1; ENSHHUP00000088149.1; ENSHHUG00000050948.1.
DR   GeneTree; ENSGT01030000234614; -.
DR   Proteomes; UP000314982; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   Gene3D; 6.10.250.2090; -; 1.
DR   Gene3D; 3.30.479.30; Band 7 domain; 1.
DR   InterPro; IPR043202; Band-7_stomatin-like.
DR   InterPro; IPR001107; Band_7.
DR   InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR   InterPro; IPR001972; Stomatin_HflK_fam.
DR   PANTHER; PTHR10264; BAND 7 PROTEIN-RELATED; 1.
DR   PANTHER; PTHR10264:SF132; PODOCIN; 1.
DR   Pfam; PF01145; Band_7; 1.
DR   PRINTS; PR00721; STOMATIN.
DR   SMART; SM00244; PHB; 1.
DR   SUPFAM; SSF117892; Band 7/SPFH domain; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000314982};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          141..300
FT                   /note="Band 7"
FT                   /evidence="ECO:0000259|SMART:SM00244"
FT   REGION          1..78
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          374..403
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        39..72
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        388..403
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   403 AA;  44902 MW;  DC80FCFBBBF71712 CRC64;
     MEKRPESASP RRTPRTGRVA KREHSGSPTS RGRRHKGTKT VRLPEEHEKR EGPKSDTQGA
     ETKGEADQEI DRPVKSTSTV VDVDNVREKE RGEENEEFMA LLESEWQEEG VKPRSLGVCE
     WLLMVLALTL VILFFPISIW FCVKVVREHE RAVIFRLGHL LRGRPRGPGL LFYLPLLDVF
     QKVDIRLKML KVPAHTVVTK DLVSTELSAV CYYRIENVAL CSTALSGVSA VLQALVQVAD
     RDVLAHHNFT HILLDRKRIA QEIQMAIDSV ACQWGIKVER AEIEDLSLPT ELQRSLAAEA
     EAKRQAQIKV IAAEGERAAC EALKASLDSL SGSPAAIHLR LLQLLHTLRT ERPALVLTLP
     SDLLTLPHDP LTLPAPAPNL APAHPIPKGG ETKEERKTDS PMM
//