ID A0A4W6BRP2_LATCA Unreviewed; 619 AA.
AC A0A4W6BRP2;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Transcription initiation factor TFIID subunit 6 {ECO:0000256|ARBA:ARBA00040091};
GN Name=LOC108893885 {ECO:0000313|Ensembl:ENSLCAP00010001998.1};
OS Lates calcarifer (Barramundi) (Holocentrus calcarifer).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangaria incertae sedis; Centropomidae; Lates.
OX NCBI_TaxID=8187 {ECO:0000313|Ensembl:ENSLCAP00010001998.1, ECO:0000313|Proteomes:UP000314980};
RN [1] {ECO:0000313|Proteomes:UP000314980}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Sai Rama Sridatta P.;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLCAP00010001998.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF6 family.
CC {ECO:0000256|ARBA:ARBA00007688}.
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DR AlphaFoldDB; A0A4W6BRP2; -.
DR Ensembl; ENSLCAT00010002065.1; ENSLCAP00010001998.1; ENSLCAG00010001094.1.
DR GeneTree; ENSGT00640000091486; -.
DR Proteomes; UP000314980; Unassembled WGS sequence.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd08050; TAF6C; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 1.25.40.770; TAF6, C-terminal HEAT repeat domain; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037796; TAF6.
DR InterPro; IPR011442; TAF6_C.
DR InterPro; IPR046344; TAF6_C_sf.
DR InterPro; IPR004823; TAF_TATA-bd_Histone-like_dom.
DR PANTHER; PTHR10221; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR PANTHER; PTHR10221:SF9; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR Pfam; PF02969; TAF; 1.
DR Pfam; PF07571; TAF6_C; 1.
DR SMART; SM00803; TAF; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000314980};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 12..78
FT /note="TATA box binding protein associated factor (TAF)
FT histone-like fold"
FT /evidence="ECO:0000259|SMART:SM00803"
FT REGION 153..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 576..619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..599
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 619 AA; 67414 MW; 3E619A465F3A4344 CRC64;
MAEERRQKQC SVILPTESMK AMAESAGVGQ LQEESCVALS EEVSYRIKEI AQDALKFMHH
GKRRKLTTSD IDNALKLKNV EPLYGFQSQE FIPFRFASGG GRELHFYEER EVDLSDIINT
PLPRVPLDVS LKAPKEQQKA ESTEPLKIVK PGQEEEATIQ GKSQGATTAD GKGKEKGLIR
LKPRSTHELS VEQQLYYKEI TEACVGSCEA KRAEALQSIA TDPGLYQMLP RFSTFISEGV
RVNVVQNNLA LLIYLMRMVK ALMDNPTLYL EKYLHELIPA VVTCIVSKQL CLRPDVDNHW
ALRDFAARLM AQSCKTFSTT TNNIQSRITK TFTKSWLDDK TQWTTRYGCI AGLAELGPDV
IKTLILPRLA VEGARIKAVM EGPVVSNIDK IGADHVQSLL LKHCASVIAK IRPQPDNVEQ
YRQDYGYLGP MLCSHVMKAR TQAALQAQQV NRTTLTITQP RPTLSVSQSG ISGSTGPRTP
SIIKVPSSLT LMSPRPGTPS QPSPPAAKYI VMATSAGAAS TQQVITLSSS QSASPVTSTV
PSATSTLQPL VKLEPGSGPG LTGSRPMQKY IVVSLPSSAS SSLEPKSSVL PTSISSTPLE
AGVKMDRSES PGASTQSPH
//
