ID A0A4W6D2U7_LATCA Unreviewed; 652 AA.
AC A0A4W6D2U7;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Premelanosome protein b {ECO:0000313|Ensembl:ENSLCAP00010019097.1};
OS Lates calcarifer (Barramundi) (Holocentrus calcarifer).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangaria incertae sedis; Centropomidae; Lates.
OX NCBI_TaxID=8187 {ECO:0000313|Ensembl:ENSLCAP00010019097.1, ECO:0000313|Proteomes:UP000314980};
RN [1] {ECO:0000313|Proteomes:UP000314980}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Sai Rama Sridatta P.;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLCAP00010019097.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PMEL/NMB family.
CC {ECO:0000256|ARBA:ARBA00025776}.
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DR AlphaFoldDB; A0A4W6D2U7; -.
DR STRING; 8187.ENSLCAP00010019097; -.
DR Ensembl; ENSLCAT00010019506.1; ENSLCAP00010019097.1; ENSLCAG00010009025.1.
DR GeneTree; ENSGT00950000183188; -.
DR InParanoid; A0A4W6D2U7; -.
DR Proteomes; UP000314980; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR045219; PKAT.
DR InterPro; IPR046846; PKAT_KLD.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR11861; MELANOCYTE PROTEIN PMEL 17-RELATED; 1.
DR PANTHER; PTHR11861:SF12; SILVER HOMOLOG (MOUSE) B; 1.
DR Pfam; PF20433; PKAT_KLD; 1.
DR Pfam; PF00801; PKD; 1.
DR SMART; SM00089; PKD; 1.
DR SUPFAM; SSF49299; PKD domain; 1.
DR PROSITE; PS50093; PKD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000314980};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..652
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5021362634"
FT TRANSMEM 583..603
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 281..315
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT REGION 332..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 376..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..414
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 652 AA; 71348 MW; A02D78BFAD9518B3 CRC64;
MIAIKRIFMS LPTFSFWSSM TSAIFLCCCI TSSNQTGAAL LLNSDTNSQR HPQDRLTHCR
QSPKTVSLVI HHGTLRCIPV WKDGDARYKE AWKGGRVSFN VGNDSPTLTG AKVTFTIDLE
FPHNQRVQPD GDVVWAEDCI INGTKYRESE PVYPAQNTDW EAVFPDGTPF KKDKKPAYVF
VWKTWGQYWQ VADGPSSSLT IATDDIPLGS YNMDIVIYHY RSKEKFIPLG YASTQFSITD
QIPFAVSLDQ VNDIVAGDMR FVQNRAIAFT ITLHDPSEYL SNADITFNWD FGDESGALIS
RELTVTHTYI SCGSFKPQVV IQAVIPDKAC DPPVDTTTKA PGPPSDQGTT VKAPALASAL
PLLVSTKATS LTVNMVPSDT EEDNAEYETS TASSTTQETP TVAKTPSPIN QDMAADSDAE
NRLTAGAKRT VTLTGQATVV VVAKRDAGDK PDDDCVIYRY GSFCTGIEVF EGIEKVEITQ
MDNAVMETPG MDKNVLDITV TCQGSHPKEV CSVILDAECL RPIHTACNMV EPSKECQLVL
RHFFNNSGVY CINVSMANDV SLAATSAKFN LVMGSGVSSS GTIAMLLGVL VLVLAVGIVA
YSYKRFKSYR RLKEEMIASG GQQLGGRAQS FWNLLNRRAA VDNCPLLQDR PV
//
