ID   A0A4W6FTR5_LATCA        Unreviewed;       456 AA.
AC   A0A4W6FTR5;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Proteasome 26S subunit, non-ATPase 12 {ECO:0000313|Ensembl:ENSLCAP00010054013.1};
OS   Lates calcarifer (Barramundi) (Holocentrus calcarifer).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangaria incertae sedis; Centropomidae; Lates.
OX   NCBI_TaxID=8187 {ECO:0000313|Ensembl:ENSLCAP00010054013.1, ECO:0000313|Proteomes:UP000314980};
RN   [1] {ECO:0000313|Proteomes:UP000314980}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Sai Rama Sridatta P.;
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLCAP00010054013.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the proteasome subunit p55 family.
CC       {ECO:0000256|ARBA:ARBA00006397}.
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DR   AlphaFoldDB; A0A4W6FTR5; -.
DR   STRING; 8187.ENSLCAP00010054013; -.
DR   Ensembl; ENSLCAT00010055419.1; ENSLCAP00010054013.1; ENSLCAG00010025136.1.
DR   GeneTree; ENSGT00940000153510; -.
DR   InParanoid; A0A4W6FTR5; -.
DR   Proteomes; UP000314980; Unassembled WGS sequence.
DR   GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000717; PCI_dom.
DR   InterPro; IPR040134; PSMD12/CSN4.
DR   InterPro; IPR040896; RPN5_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10855:SF1; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12; 1.
DR   PANTHER; PTHR10855; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4; 1.
DR   Pfam; PF01399; PCI; 1.
DR   Pfam; PF18098; RPN5_C; 1.
DR   SMART; SM00088; PINT; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   3: Inferred from homology;
KW   Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW   Reference proteome {ECO:0000313|Proteomes:UP000314980}.
FT   DOMAIN          242..420
FT                   /note="PCI"
FT                   /evidence="ECO:0000259|PROSITE:PS50250"
SQ   SEQUENCE   456 AA;  52917 MW;  70EA01D5234EAA9E CRC64;
     MSEERSERSD GRIVKMEIDY SSTVDQRLPE CEKMAKEGKL QEAIESLLSL EKQTRTASDM
     VSTSRILVAV VQMCYEAKDW DALNENIMLL TKRRSQLKQA VAKMVQECYK YVDAMTDLTI
     KLRLIDTLRT VTAGKIYVEI ERARLTKTLA SIKEQSGEVK EAASILQELQ VETYGSMEKK
     EKVEFILEQM RLCIAVKDYI RTQIISKKIN TKFFQEEGTE ESKLKYYNLM IQVDQHEGSY
     LSICKHYRAI YDTPCILEDS SKWQQALKSV VLYVILSPYD NEQSDLVHRI SGIFHHILPS
     IPRDLLKQFT TMELMRWASL VEDYGKELRE GSPDSPATDV FSYSEEGEKR WKDLKNRVVE
     HNIRIMAKYY TRITMKRMAG LLDLSIDESE EFLSSLVVNK TIYAKVDRLA GIINFQRPKD
     PNDLLNDWSH KLNSLMSLVN KTTHLIAKEE MIHNLQ
//