ID   A0A4W6FUW5_LATCA        Unreviewed;       514 AA.
AC   A0A4W6FUW5;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Dynein cytoplasmic 1 intermediate chain 2 {ECO:0000313|Ensembl:ENSLCAP00010054694.1};
GN   Name=DYNC1I2 {ECO:0000313|Ensembl:ENSLCAP00010054694.1};
OS   Lates calcarifer (Barramundi) (Holocentrus calcarifer).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangaria incertae sedis; Centropomidae; Lates.
OX   NCBI_TaxID=8187 {ECO:0000313|Ensembl:ENSLCAP00010054694.1, ECO:0000313|Proteomes:UP000314980};
RN   [1] {ECO:0000313|Proteomes:UP000314980}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Sai Rama Sridatta P.;
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLCAP00010054694.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the dynein intermediate chain family.
CC       {ECO:0000256|ARBA:ARBA00011059}.
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DR   AlphaFoldDB; A0A4W6FUW5; -.
DR   Ensembl; ENSLCAT00010056126.1; ENSLCAP00010054694.1; ENSLCAG00010025443.1.
DR   GeneTree; ENSGT00940000155442; -.
DR   Proteomes; UP000314980; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005868; C:cytoplasmic dynein complex; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR025956; DYNC1I1/DYNC1I2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR12442:SF37; CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 2; 1.
DR   PANTHER; PTHR12442; DYNEIN INTERMEDIATE CHAIN; 1.
DR   Pfam; PF11540; Dynein_IC2; 1.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000314980};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT   REGION          1..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        39..53
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        78..96
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   514 AA;  57720 MW;  A9A029FED1570D93 CRC64;
     VTLHWDSDPS TLQLHSDSEL GRGTPKLGMA KVTQVDFPPR ETVSYTKETQ TPVMTQQKEE
     EEEEEEIAPP QPVVETPTEK PDQKEEEEAP PHELTEEEKL QILHSEEFVN FFDHSTRIIE
     RALSEHVDLF FDYSGRDLEE KEGEIQAGAK LSLNRQFMDE RWSKHRVVTC LDWSPQYPEL
     LVASYNNNED APHEPDGVAL VWNMKYKKAT PEYVFHCQSA VMSAAFAKFH PNVVVGGTYS
     GQIVLWDNRS NKRTPVQRTP LSAAAHTHPV YCVNVVGTQN AHNLISISTD GKMCSWSLDM
     LSQPQDSMEL VFKQSKAVAV TSMSFPLGDV NNFVVGSEDG SVYMSCRHGS KAGISEMFEG
     HHGPITGIHC HTAAGPLDFS HLFVTSSFDW TVKLWSTKNN KPLYSFEDNS DYVYDVMWSP
     THPALFACVD GVGHLDLWNL NNDTEVPTAS VTVEGNPALN RVRWAHSGRE IAVGDSDGRI
     RVYDVGEVSR RDSAFYLSQF MIVLLCHSSV LLQT
//