ID A0A4W6G165_LATCA Unreviewed; 1097 AA.
AC A0A4W6G165;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=LIM and calponin homology domains 1 {ECO:0000313|Ensembl:ENSLCAP00010056709.1};
GN Name=LIMCH1 {ECO:0000313|Ensembl:ENSLCAP00010056709.1};
OS Lates calcarifer (Barramundi) (Holocentrus calcarifer).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangaria incertae sedis; Centropomidae; Lates.
OX NCBI_TaxID=8187 {ECO:0000313|Ensembl:ENSLCAP00010056709.1, ECO:0000313|Proteomes:UP000314980};
RN [1] {ECO:0000313|Proteomes:UP000314980}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Sai Rama Sridatta P.;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLCAP00010056709.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A4W6G165; -.
DR Ensembl; ENSLCAT00010058255.1; ENSLCAP00010056709.1; ENSLCAG00010026404.1.
DR GeneTree; ENSGT00950000183159; -.
DR Proteomes; UP000314980; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd21278; CH_LIMCH1; 1.
DR CDD; cd08368; LIM; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR031865; DUF4757.
DR InterPro; IPR003096; SM22_calponin.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR15551:SF3; LIM AND CALPONIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR15551; LIM DOMAIN ONLY 7; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF15949; DUF4757; 1.
DR Pfam; PF00412; LIM; 1.
DR PRINTS; PR00888; SM22CALPONIN.
DR SMART; SM00033; CH; 1.
DR SMART; SM00132; LIM; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000314980};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 23..140
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 1025..1091
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 476..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 807..1027
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 402..432
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 187..208
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..223
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 232..259
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..286
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 583..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 647..661
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..679
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 689..759
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 807..855
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 857..884
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 886..924
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 925..958
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 968..982
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1097 AA; 121384 MW; D3E79D9FE03180E3 CRC64;
MASPVADIGQ SHQHHPVTES AAESAFQEAQ KWIEAVTGRC FGDKDFRGGL ENGILLCELL
SSIKPGLVKK INRLPTPIAG LDNLSVFLRG CEELGLKGSQ LFDPGDLQDT STRPTAKGSD
CSRKLKNVLI TIYWLGRAAN GCTSYNGPTL DLKEFEGLLS QMRKEAEEAE SPKRSIRDSG
YIDCWDSERS DSLSPPRHGR EDSFDSLDSF GSRSRQTPSP DVLVARGSSD GRGSDSESDG
APHRKMPDVR KDDMLARRTS VSEPRTAMPF NQYLPNKSNQ SGYVPTPLRK KKNDKEEGGR
KSWSTATSPI GGDRPFRSVS MIDMRGEEEA ILQPHSQVRH ELMHNQYNRM KEEEDHWQDD
LARWKSRRRS ISQDLIKKEE ERKMMEQLMS GDTCSSQRRR SIKTYREIVE DKERREEELR
QAYRRAKTQE EASAILQRYA QRFSISEAVL ERLQLPKLLD RSISADPSFP CSPFPLSLSA
SPTTPDPFDV DPNGPLRYLR QQSAPAPKFT STLEARIEEF PKDLSSHQRP QIRSRSSEPP
STRALSPKPV PLLTPKPYFD SRAMASELWA CKADGLLRVN GNIGSDNVPT TPESQGRESP
PQFQASPSKT SNSTVDAASS AASPIHSPHA SPGGGSPVST KDKEVQGGTE AASEDVRGEK
VTDNSTPPSR PTSLPTELQK PEDSFEKTRG QTAAVQEEKE SNVEAQPTPP TEAKQEQAKS
EPTSQNISSL VQSGVSVQQS QPVTLQASVP SSNELSQRRE DMPSLAAPGS SGYHPPRETT
AEFANSVRSP LATSNPKLRW EFFIPPEGAE KDRRGNEKYR REQEKLKEEW EKAQREVAEE
ERKYHEEERR ILEETVTPLT PRSSALPSPS RGELSSTSEP QDTIVRSLAD WERKQELLER
QSRGSTENME GKRRENDRTS DISTADDSMK TGRSLGSQST SQPETLGHSL QNGQKPPPMP
AKSSTPMKKQ DHTADSNRPS RPAGDRRSGP IDNNMSRSSS KPPAACPPTP DTLPPAPNRS
VSGKKLCSSC GQPLGKGAAM IIETLSLYFH IHCFKCGVCK GQLGDTTTGT DVRIRNGLLN
CHQCYIRSRS AGQPTTL
//
