ID A0A4W6G601_LATCA Unreviewed; 165 AA.
AC A0A4W6G601;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Epithelial membrane protein 3b {ECO:0000313|Ensembl:ENSLCAP00010058900.1};
GN Name=LOC108891696 {ECO:0000313|Ensembl:ENSLCAP00010058900.1};
OS Lates calcarifer (Barramundi) (Holocentrus calcarifer).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangaria incertae sedis; Centropomidae; Lates.
OX NCBI_TaxID=8187 {ECO:0000313|Ensembl:ENSLCAP00010058900.1, ECO:0000313|Proteomes:UP000314980};
RN [1] {ECO:0000313|Proteomes:UP000314980}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Sai Rama Sridatta P.;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLCAP00010058900.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU363088}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU363088}.
CC -!- SIMILARITY: Belongs to the PMP-22/EMP/MP20 family.
CC {ECO:0000256|ARBA:ARBA00006864, ECO:0000256|RuleBase:RU363088}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU363088}.
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DR RefSeq; XP_018544477.1; XM_018688961.1.
DR AlphaFoldDB; A0A4W6G601; -.
DR STRING; 8187.ENSLCAP00010058900; -.
DR Ensembl; ENSLCAT00010060506.1; ENSLCAP00010058900.1; ENSLCAG00010027459.1.
DR GeneID; 108891696; -.
DR KEGG; lcf:108891696; -.
DR GeneTree; ENSGT00950000182696; -.
DR InParanoid; A0A4W6G601; -.
DR OrthoDB; 4195542at2759; -.
DR Proteomes; UP000314980; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR InterPro; IPR004032; PMP22_EMP_MP20.
DR PANTHER; PTHR10671:SF8; EPITHELIAL MEMBRANE PROTEIN 3; 1.
DR PANTHER; PTHR10671; EPITHELIAL MEMBRANE PROTEIN-RELATED; 1.
DR Pfam; PF00822; PMP22_Claudin; 1.
DR PRINTS; PR01453; EPMEMFAMILY.
DR PROSITE; PS01221; PMP22_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363088};
KW Reference proteome {ECO:0000313|Proteomes:UP000314980};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363088};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363088}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..165
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5021493185"
FT TRANSMEM 62..84
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363088"
FT TRANSMEM 96..121
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363088"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363088"
SQ SEQUENCE 165 AA; 18790 MW; CC2D0153E15BCB01 CRC64;
MAYLLMFVTL LHLITLAMLF IATMEKSWWV WDGMENSDLW YNCRFDNSTG TWLCASSKET
EWLQAVQVLM VLSVVFSSVS FLVFLGQLFT MSKGGLFYFT GLCQVFAGLT AFSAALIYTL
HNKEILPTSK ELTSGRFGYC FILAWVCVPL LLCSGVIYIH LRKKE
//
