ID A0A4X2K5J1_VOMUR Unreviewed; 698 AA.
AC A0A4X2K5J1;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=FERM domain containing 7 {ECO:0000313|Ensembl:ENSVURP00010004465.1};
GN Name=FRMD7 {ECO:0000313|Ensembl:ENSVURP00010004465.1};
OS Vombatus ursinus (Common wombat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Diprotodontia; Vombatidae; Vombatus.
OX NCBI_TaxID=29139 {ECO:0000313|Ensembl:ENSVURP00010004465.1, ECO:0000313|Proteomes:UP000314987};
RN [1] {ECO:0000313|Proteomes:UP000314987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Yazar S.;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSVURP00010004465.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A4X2K5J1; -.
DR STRING; 29139.ENSVURP00010004465; -.
DR Ensembl; ENSVURT00010005072.1; ENSVURP00010004465.1; ENSVURG00010003533.1.
DR GeneTree; ENSGT00940000158972; -.
DR OMA; PYIPCTS; -.
DR Proteomes; UP000314987; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0030426; C:growth cone; IEA:Ensembl.
DR GO; GO:0043025; C:neuronal cell body; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0051497; P:negative regulation of stress fiber assembly; IEA:Ensembl.
DR GO; GO:0010592; P:positive regulation of lamellipodium assembly; IEA:Ensembl.
DR GO; GO:0051057; P:positive regulation of small GTPase mediated signal transduction; IEA:Ensembl.
DR GO; GO:0010975; P:regulation of neuron projection development; IEA:Ensembl.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13193; FERM_C_FARP1-like; 1.
DR CDD; cd17188; FERM_F1_FRMD7; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014847; FA.
DR InterPro; IPR041788; FARP1/FARP2/FRMD7_FERM_C.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45858; FERM DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45858:SF1; FERM DOMAIN-CONTAINING PROTEIN 7; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000314987}.
FT DOMAIN 2..282
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 619..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..634
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 698 AA; 79532 MW; 126F0F92056CEB34 CRC64;
MLHLRVQFLD DSQKIFMVDQ KSSGKALFNL SCCHLNLAEK EYFGLEFRSQ SGNNVWLELL
KPITKQVKNP KEILFKFMVK FFPVDPGHLR DELTRYLFAL QIKKDLAQGT LPCSDDCTAL
LVSHILQSEL GDFHEETDRK HLEQNHYLPN QGGLDSKILR FHQRHIGKSP AESDIQLLDI
ARKLEMYGIR PHPASDGEGT QIHLAVAHMG VLVLRGNTKI NTFNWAKIRK LSFKRKHFLI
KLHASISVLY KDTLEFTMAS RDACKAFWKT CVEYHAFFRL SEEPKSKPKT LFCSKGSSFR
YSGRTQRQLL EYGKKGRLKS LPFERKHYPP QYHERQCRSS PDLLSDVAKQ VEDLHLVYGG
GCYRSVNGVH ASEPTLDSRR RNSTVEVTFA AEFERSKPEA DPTLLHQSQS SSTFPFLYTK
PDFNADPEPD ISIGKSPLNS FQTSSEFAKG NTSVSGNTRG VVPPRQQLTY TDLPYIPNVS
QQVDIVPPQV FFYVDQPPQV PRRSPAMATL GKAAKRSPHD ARREPFQHDF QELEEALART
SSGDSPNRGV EDDDRTLEDA FEYRVQEHTP KRSHSHSDMK TIRFPFGSEF QPLGPCPALS
RKADFFTYML AQQEFPEVLQ SRSTADQYSG SEPSDSEPEM PHPDYYALCD KTVRLPMTRI
RLSSASLQLD EAEEEASFTT PAAHSGRTTL KPRNYFLA
//
