ID   A0A4X2KCX2_VOMUR        Unreviewed;       720 AA.
AC   A0A4X2KCX2;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Jade family PHD finger 2 {ECO:0000313|Ensembl:ENSVURP00010009784.1};
GN   Name=JADE2 {ECO:0000313|Ensembl:ENSVURP00010009784.1};
OS   Vombatus ursinus (Common wombat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Metatheria; Diprotodontia; Vombatidae; Vombatus.
OX   NCBI_TaxID=29139 {ECO:0000313|Ensembl:ENSVURP00010009784.1, ECO:0000313|Proteomes:UP000314987};
RN   [1] {ECO:0000313|Proteomes:UP000314987}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Yazar S.;
RL   Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSVURP00010009784.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A4X2KCX2; -.
DR   Ensembl; ENSVURT00010011100.1; ENSVURP00010009784.1; ENSVURG00010007533.1.
DR   GeneTree; ENSGT00940000158570; -.
DR   Proteomes; UP000314987; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd15680; PHD_JADE2; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR   InterPro; IPR019542; Enhancer_polycomb-like_N.
DR   InterPro; IPR034732; EPHD.
DR   InterPro; IPR039548; JADE2_PHD.
DR   InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR019787; Znf_PHD-finger.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR13793:SF84; E3 UBIQUITIN-PROTEIN LIGASE JADE-2; 1.
DR   PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR   Pfam; PF10513; EPL1; 1.
DR   Pfam; PF13831; PHD_2; 1.
DR   Pfam; PF13832; zf-HC5HC2H_2; 1.
DR   SMART; SM00249; PHD; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   PROSITE; PS51805; EPHD; 1.
DR   PROSITE; PS01359; ZF_PHD_1; 1.
DR   PROSITE; PS50016; ZF_PHD_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000314987};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00146}.
FT   DOMAIN          195..245
FT                   /note="PHD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50016"
FT   DOMAIN          247..369
FT                   /note="PHD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51805"
FT   REGION          1..47
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          419..454
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          532..720
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..36
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        532..564
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        584..604
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        640..655
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        684..710
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   720 AA;  80694 MW;  FFC323602654F220 CRC64;
     MEEKRRKYSI SSDNSDTTDS HTTSNSRCSK IPTNKPSWPR QKEKKPSEVF RTDLITAMKI
     PDSYQLSPDE YYILADPWRQ EWEKGVQVPA GTEAIPEPVV RVLPLLEHTP GQISPSSLSG
     SELSEVTRPY SRYDLDEIDA YWLELVNLEL KEMEKPELDE MTMERVLEEL ETVCHQNMNM
     AIETEEGLGI EYDEDVVCDV CRSPEGEDGN EMVFCDKCNV CVHQACYGIL KVPTGSWLCR
     TCALGVQPRC LLCPKRGGAL KPTRSGTKWV HVSCALWIPE VSIGCPEKME PITKISHIPA
     SRWALSCSLC RECTGTCIQV DAQMKAFPAL AAWRERGKMV WEGDEVGNRA YLAITALLGN
     RKGSSHSHSV RWEIFLVSPQ VRNLCYMVTR REKMKHSICK LQEQIFHLQM RLIEKDLYRE
     QPGKRSKGKK NDSKWKGRDS RKASPEKKEK MKPGNELVLG QLGLSTSFPI DGTFFNSWLA
     QSVQITTENM AMSEWSLNNG HHEDNTSGLL SEELLQDEET LLSIMMDHSL KSPFKHSDTT
     KKAQSKARPA NKKKVPRDSL GSLLSDHPED SGASGEVRKT PKRGPSNHSP SPKAHDSSVL
     AGSRSSPHED KETVDATPLE TNSPLQVPGS LGSPKTVVRF RLPKEGRETK KLPNPKPEAM
     NRPPSGERPK VTLHFDNETD GYFSDAEMSD SDSEPGSGRV QLSQKDSGNE EVVRMSVLAS
//