ID   A0A4Y0BJX2_ANOFN        Unreviewed;       512 AA.
AC   A0A4Y0BJX2;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   13-SEP-2023, entry version 13.
DE   RecName: Full=CCAAT-binding factor domain-containing protein {ECO:0000259|Pfam:PF03914};
OS   Anopheles funestus (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=62324 {ECO:0000313|EnsemblMetazoa:AFUN020904-PA, ECO:0000313|Proteomes:UP000075900};
RN   [1] {ECO:0000313|Proteomes:UP000075900}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=FUMOZ {ECO:0000313|Proteomes:UP000075900};
RX   PubMed=21129198; DOI=10.1186/1756-3305-3-117;
RA   Sinka M.E., Bangs M.J., Manguin S., Coetzee M., Mbogo C.M., Hemingway J.,
RA   Patil A.P., Temperley W.H., Gething P.W., Kabaria C.W., Okara R.M.,
RA   Van Boeckel T., Godfray H.C., Harbach R.E., Hay S.I.;
RT   "The dominant Anopheles vectors of human malaria in Africa, Europe and the
RT   Middle East: occurrence data, distribution maps and bionomic precis.";
RL   Parasit. Vectors 3:117-117(2010).
RN   [2] {ECO:0000313|Proteomes:UP000075900}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=FUMOZ {ECO:0000313|Proteomes:UP000075900};
RX   PubMed=31157884; DOI=10.1093/gigascience/giz063;
RA   Ghurye J., Koren S., Small S.T., Redmond S., Howell P., Phillippy A.M.,
RA   Besansky N.J.;
RT   "A chromosome-scale assembly of the major African malaria vector Anopheles
RT   funestus.";
RL   Gigascience 8:0-0(2019).
RN   [3] {ECO:0000313|EnsemblMetazoa:AFUN020904-PA}
RP   IDENTIFICATION.
RC   STRAIN=FUMOZ {ECO:0000313|EnsemblMetazoa:AFUN020904-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the CBF/MAK21 family.
CC       {ECO:0000256|ARBA:ARBA00007797}.
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DR   AlphaFoldDB; A0A4Y0BJX2; -.
DR   STRING; 62324.A0A4Y0BJX2; -.
DR   EnsemblMetazoa; AFUN020904-RA; AFUN020904-PA; AFUN020904.
DR   VEuPathDB; VectorBase:AFUN020904; -.
DR   VEuPathDB; VectorBase:AFUN2_012079; -.
DR   Proteomes; UP000075900; Unassembled WGS sequence.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR   InterPro; IPR005612; CCAAT-binding_factor.
DR   InterPro; IPR027193; Noc4.
DR   PANTHER; PTHR12455; NUCLEOLAR COMPLEX PROTEIN 4; 1.
DR   PANTHER; PTHR12455:SF0; NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG; 1.
DR   Pfam; PF03914; CBF; 1.
PE   3: Inferred from homology;
FT   DOMAIN          301..449
FT                   /note="CCAAT-binding factor"
FT                   /evidence="ECO:0000259|Pfam:PF03914"
SQ   SEQUENCE   512 AA;  58352 MW;  C94ED424AC4D50EB CRC64;
     MSLPFVPKLS QISSGKAVSK QLKKKATEFL ACTRATTTLG EILEYYKECL ARKAPITPCL
     LTLEYLFTQL FQRADIRPED IDAQPTYVPS AKDPQANHRQ WLLAQYQETC GLVIDGMHHE
     KESEACQALA TAMKLLAAQC LQQPEADRFP VAGLKQILTA MLSSECLNKH LFSRFLEYSS
     YLDVIFYCWK TVPSLVPRNC TPTDAFKQNF LLLLDAIMFG KDKMKERDSE LCVKLGDSFD
     YAYVRKQINR TWGFVMNWEH SEMVHEQLLI LLLEKVFVHL DKPVLLTDFL MDSLDVGGTV
     SVLALQGVFV LIQQHNLTYP NIYEKLYSMF EPEIFHTKFK ARLFYLADIF LSSSHLPEGL
     VAAFVKRLAR LALIAPPQDI VIILRFVGNL ILRHPALKRL IFHPTGGEAS SDPYVMEERD
     PMKSKALESS LWELAALQNH VLPSVASAAR FISNPLPSVE WDLSEVLEIN ENDIFHKEIV
     SKTKEFFVNI DRPTGMFGYC GGQMASQYWK LF
//