ID A0A4Y3FWE3_9CYAN Unreviewed; 1254 AA.
AC A0A4Y3FWE3;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Nitrate reductase {ECO:0000313|EMBL:GCE65752.1};
GN ORFNames=OMCYN_01698 {ECO:0000313|EMBL:GCE65752.1};
OS cyanobiont of Ornithocercus magnificus.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales.
OX NCBI_TaxID=2496102 {ECO:0000313|EMBL:GCE65752.1, ECO:0000313|Proteomes:UP000321200};
RN [1] {ECO:0000313|EMBL:GCE65752.1, ECO:0000313|Proteomes:UP000321200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OmCyn01 {ECO:0000313|EMBL:GCE65752.1,
RC ECO:0000313|Proteomes:UP000321200};
RX PubMed=31235587; DOI=10.1073/pnas.1902538116;
RA Nakayama T., Nomura M., Takano Y., Tanifuji G., Shiba K., Inaba K.,
RA Inagaki Y., Kawata M.;
RT "Single-cell genomics unveiled a cryptic cyanobacterial lineage with a
RT worldwide distribution hidden by a dinoflagellate host.";
RL Proc. Natl. Acad. Sci. U.S.A. 116:15973-15978(2019).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCE65752.1}.
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DR EMBL; BIMP01000004; GCE65752.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4Y3FWE3; -.
DR OrthoDB; 9803192at2; -.
DR Proteomes; UP000321200; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd02791; MopB_CT_Nitrate-R-NapA-like; 1.
DR CDD; cd02754; MopB_Nitrate-R-NapA-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.90.480.20; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR Gene3D; 3.30.413.10; Sulfite Reductase Hemoprotein, domain 1; 2.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR041957; CT_Nitrate-R-NapA-like.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR005117; NiRdtase/SiRdtase_haem-b_fer.
DR InterPro; IPR036136; Nit/Sulf_reduc_fer-like_dom_sf.
DR InterPro; IPR006067; NO2/SO3_Rdtase_4Fe4S_dom.
DR InterPro; IPR045854; NO2/SO3_Rdtase_4Fe4S_sf.
DR InterPro; IPR006066; NO2/SO3_Rdtase_FeS/sirohaem_BS.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR Pfam; PF01077; NIR_SIR; 2.
DR Pfam; PF03460; NIR_SIR_ferr; 2.
DR PRINTS; PR00397; SIROHAEM.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR SUPFAM; SSF56014; Nitrite and sulphite reductase 4Fe-4S domain-like; 2.
DR SUPFAM; SSF55124; Nitrite/Sulfite reductase N-terminal domain-like; 2.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000321200}.
FT DOMAIN 5..73
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 1254 AA; 138552 MW; 70F91484679E5F36 CRC64;
MTIVSGSVRS QCPYCGVGCG LEMLPPTQLG KPTRLDADGN PMWTARGDRS HPSSLGQLCI
KGASVGEALS CGRLYQPMYR PSLDVDFQPV SWDTALNRIT DQICSSLQTK GPSAIAMYGS
GQFHTEDYYL AQKLFKGALG TNNFDANSRL CMSSAVAGYI RSLGSDGPPC CYEDLDHCTV
AFLIGTNTAE CHPVLFQRLI RRKKKDPSSL VLIVIDPRQT DTAKNADIHL QIAPGTDLAL
LHGIAHLVLR SNRQDQAFIN KATENYDAFS KEVNRWTPGL VAKFCRISEK QLQDVAQLWC
CDQNILSLWS MGINQRREGT AIVCGVINLH LLTGQIGKEG AGPFSLTGQP NAMGGREAGG
LAQLLPGYRL TTNSQHRADL EEAWNFPAGS IAAEPGLVAY QQIEAMAKGE IDLWWVAATN
PLVSMPNLKQ VKAAAQRCPF VVVSEVYAGS ETAFYSHLLL PACQWSEKAG VMTNSERRVT
YCPAYRPRHG QSMPDWQIFA EVGRRLGFEE QFAFDSAAEV YTEFTSITKG RICDVSGLSH
ELLKQNGPQQ WPFPSGSQPT KDAKRLYSDH HFPTESGLAH FTADQPLGIA EAPCNDYPLV
LTVGRYLGQW HTMTRTGKVR RLQLMHPEPL LEINPTDAQK FKLCDKEVAV VSSRRSYLTV
RVKVTDRILI GTVFLPMHWG FTQEHACEVN MLIYGQVCPI SKQPELKACA VMAAPATPKL
PVPTVKQEQT MAINSSSLTS TRSYLDGRKL NKIEQDKANK DGLLVGSEIE RFAQLGWEQM
NKTDLELRLK WYGIFWRPKT PGKFMLRLRI PNGILSEYQL RIVASIVGRY GDASSCDITT
RQNLQLRGIL IGDLPEILRR LKKAGLSSIQ SGFDNPRNIT GNPLAGIDPL EIVDTRPYTT
ELQNFLTNNC EGNPEFSNLP RKWNAAVAGA KDNFLLHNDI IFHPVENDGV MGFGVWIAGI
LSSQMNAYAV PLNVWVKTDQ ICMITDAVIK IWRDNGERNK RNRGRFRFYL EEVGLDAFRS
MVEEFLGQQL TPDPGSVFND TPRSHLGIHP QKQKGFYFAG LHVPVGRLTA EDLQDLATAS
LDYGSGEVRL TEDQNVIIVG LSEDKLSSFR NDFLLQRFPL EPRSITAGTV SCTGNTYCSF
ALANTKEQAV KTSKKLDSEL DLPEEVKIHW TGCPNSCGQA YMGAIGLTGT KVRNSKGVID
DGYTITVGGS QGANPKIGEV YKKSVPAEEI GDSLRKLLID KFGAVPTQHE VPDS
//
