ID   A0A4Y3TX39_9PROT        Unreviewed;       440 AA.
AC   A0A4Y3TX39;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=rRNA cytosine-C5-methylase {ECO:0000313|EMBL:GEB86019.1};
GN   ORFNames=APE01nite_18160 {ECO:0000313|EMBL:GEB86019.1};
OS   Acetobacter peroxydans.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Acetobacter.
OX   NCBI_TaxID=104098 {ECO:0000313|EMBL:GEB86019.1, ECO:0000313|Proteomes:UP000317730};
RN   [1] {ECO:0000313|EMBL:GEB86019.1, ECO:0000313|Proteomes:UP000317730}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 13755 {ECO:0000313|EMBL:GEB86019.1,
RC   ECO:0000313|Proteomes:UP000317730};
RA   Hosoyama A., Uohara A., Ohji S., Ichikawa N.;
RT   "Whole genome shotgun sequence of Acetobacter peroxydans NBRC 13755.";
RL   Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. RsmB/NOP family. {ECO:0000256|ARBA:ARBA00007494,
CC       ECO:0000256|PROSITE-ProRule:PRU01023}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GEB86019.1}.
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DR   EMBL; BJMV01000009; GEB86019.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A4Y3TX39; -.
DR   OrthoDB; 9810297at2; -.
DR   Proteomes; UP000317730; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR018314; Fmu/NOL1/Nop2p_CS.
DR   InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR   InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR   InterPro; IPR023267; RCMT.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR22807:SF77; SUN PROTEIN; 1.
DR   Pfam; PF01189; Methyltr_RsmB-F; 1.
DR   PRINTS; PR02008; RCMTFAMILY.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS01153; NOL1_NOP2_SUN; 1.
DR   PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW   ProRule:PRU01023}; Reference proteome {ECO:0000313|Proteomes:UP000317730};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU01023};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PROSITE-ProRule:PRU01023};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW   ProRule:PRU01023}.
FT   DOMAIN          154..429
FT                   /note="SAM-dependent MTase RsmB/NOP-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51686"
FT   ACT_SITE        368
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         268
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         315
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ   SEQUENCE   440 AA;  48364 MW;  EC0CD6DB71D0C96E CRC64;
     MTPSARLAAS IDLLAAMEAA PRKPADAVAN SFFRERRYIG GGDRRAISGL VWDVMRGWRR
     LSWWLQKQNL PVSARLLCGA RLVLDGMAVS AVANLYAEGR YATGVLERHE WDGFIAMQDK
     PLDSPDMPRA VRLELPDWLL PRLEETFGPA LETEVKALSG EAPLDLRVNT LLADRAEARK
     ALAREGLHAE PTPHSPWGLR LEGRLPVTAS VPFRDGRVEI QDEGSQLVAA MTAAGPEMRV
     LDYCAGAGGK TLAMAMMMNN RGHIVACDVS EPRLDGAVRR LRRAGVHNVE RHLLGVTGDK
     WAKRRAASFD RVLVDAPCSG TGTWRRNPDA RFRTTETDLA ELLVKQAAIM DRASALVRPG
     GRMIYATCSL LKAENADQVH AFLARHPDFR LVPSEAPDLP ESLRHESMIS LTPARDETDG
     FFGAVMERVP TQDEASTSQA
//