ID A0A4Y5FHL7_9CAUD Unreviewed; 245 AA.
AC A0A4Y5FHL7;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Deoxyguanosine kinase {ECO:0000313|EMBL:QBJ03504.1};
GN ORFNames=B521_0154 {ECO:0000313|EMBL:QBJ03504.1};
OS Lactobacillus phage 521B.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Herelleviridae; Tybeckvirus; Tybeckvirus tv521B.
OX NCBI_TaxID=2510942 {ECO:0000313|EMBL:QBJ03504.1, ECO:0000313|Proteomes:UP000308874};
RN [1] {ECO:0000313|EMBL:QBJ03504.1, ECO:0000313|Proteomes:UP000308874}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Feyereisen M., Mahony J., O'Sullivan T., van Sinderen D.;
RT "Isolation of virulent Lactobacillus brevis phages.";
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; MK504443; QBJ03504.1; -; Genomic_DNA.
DR Proteomes; UP000308874; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019136; F:deoxynucleoside kinase activity; IEA:InterPro.
DR GO; GO:0071897; P:DNA biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01673; dNK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002624; DCK/DGK.
DR InterPro; IPR031314; DNK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10513; DEOXYNUCLEOSIDE KINASE; 1.
DR PANTHER; PTHR10513:SF15; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL; 1.
DR Pfam; PF01712; dNK; 1.
DR PIRSF; PIRSF000705; DNK; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRSR:PIRSR000705-
KW 3}; DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW Kinase {ECO:0000313|EMBL:QBJ03504.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRSR:PIRSR000705-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000308874};
KW Transferase {ECO:0000313|EMBL:QBJ03504.1}.
FT DOMAIN 3..213
FT /note="Deoxynucleoside kinase"
FT /evidence="ECO:0000259|Pfam:PF01712"
FT ACT_SITE 77
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-1"
FT BINDING 7..15
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
FT BINDING 31
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 43
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 54
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 78
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 83
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 144..148
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
FT BINDING 153
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
SQ SEQUENCE 245 AA; 28017 MW; 8D72E01013889493 CRC64;
MIITLSGMIG SGKSTLTTIL SDYLGTPAYY ESVTDNPILK LFYKDPKRYA FLLQIYFLNT
RFSSMKQALK TNNSIMDRSI YEDSLFFHTN ASLGRVGVGD DAKKEVSVYD NLLENMLEEI
KGMPKKSPDL MIGIKVSYET MIKRINLRGR EFEQPKNDPG LVSYYNRLLD EYDKFFNGGY
NASPILIIDG DKYDFVDNEE DREEVLNQIS DKLKSMGLLD SSFVGKEYSR NQVDNMLDKV
QSVIV
//
