ID A0A4Y7ICZ1_PAPSO Unreviewed; 886 AA.
AC A0A4Y7ICZ1;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=Coatomer subunit gamma {ECO:0000256|PIRNR:PIRNR037093};
GN ORFNames=C5167_038195 {ECO:0000313|EMBL:RZC45259.1};
OS Papaver somniferum (Opium poppy).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Papaveraceae; Papaveroideae;
OC Papaver.
OX NCBI_TaxID=3469 {ECO:0000313|EMBL:RZC45259.1, ECO:0000313|Proteomes:UP000316621};
RN [1] {ECO:0000313|EMBL:RZC45259.1, ECO:0000313|Proteomes:UP000316621}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. HN1 {ECO:0000313|Proteomes:UP000316621};
RC TISSUE=Leaves {ECO:0000313|EMBL:RZC45259.1};
RX PubMed=30166436; DOI=.1126/science.aat4096;
RA Guo L., Winzer T., Yang X., Li Y., Ning Z., He Z., Teodor R., Lu Y.,
RA Bowser T.A., Graham I.A., Ye K.;
RT "The opium poppy genome and morphinan production.";
RL Science 362:343-347(2018).
CC -!- FUNCTION: The coatomer is a cytosolic protein complex that binds to
CC dilysine motifs and reversibly associates with Golgi non-clathrin-
CC coated vesicles, which further mediate biosynthetic protein transport
CC from the ER, via the Golgi up to the trans Golgi network. Coatomer
CC complex is required for budding from Golgi membranes, and is essential
CC for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
CC {ECO:0000256|PIRNR:PIRNR037093}.
CC -!- SUBUNIT: Oligomeric complex. {ECO:0000256|PIRNR:PIRNR037093}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR037093}. Golgi
CC apparatus membrane {ECO:0000256|ARBA:ARBA00004255,
CC ECO:0000256|PIRNR:PIRNR037093}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004255, ECO:0000256|PIRNR:PIRNR037093};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004255,
CC ECO:0000256|PIRNR:PIRNR037093}. Cytoplasmic vesicle, COPI-coated
CC vesicle membrane {ECO:0000256|PIRNR:PIRNR037093}; Peripheral membrane
CC protein {ECO:0000256|PIRNR:PIRNR037093}; Cytoplasmic side
CC {ECO:0000256|PIRNR:PIRNR037093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the COPG family. {ECO:0000256|ARBA:ARBA00010720,
CC ECO:0000256|PIRNR:PIRNR037093}.
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DR EMBL; CM010715; RZC45259.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4Y7ICZ1; -.
DR STRING; 3469.A0A4Y7ICZ1; -.
DR EnsemblPlants; RZC45259; RZC45259; C5167_038195.
DR Gramene; RZC45259; RZC45259; C5167_038195.
DR OMA; IEDCEYN; -.
DR OrthoDB; 5260816at2759; -.
DR Proteomes; UP000316621; Chromosome 1.
DR GO; GO:0030126; C:COPI vesicle coat; IEA:InterPro.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.1480; Coatomer, gamma subunit, appendage domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.310.10; TATA-Binding Protein; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR009028; Coatomer/calthrin_app_sub_C.
DR InterPro; IPR032154; Coatomer_g_Cpla.
DR InterPro; IPR017106; Coatomer_gsu.
DR InterPro; IPR013040; Coatomer_gsu_app_Ig-like_dom.
DR InterPro; IPR037067; Coatomer_gsu_app_sf.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR10261; COATOMER SUBUNIT GAMMA; 1.
DR PANTHER; PTHR10261:SF0; COATOMER SUBUNIT GAMMA-2; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF16381; Coatomer_g_Cpla; 1.
DR Pfam; PF08752; COP-gamma_platf; 1.
DR PIRSF; PIRSF037093; Coatomer_gamma_subunit; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF55711; Subdomain of clathrin and coatomer appendage domain; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR037093};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329,
KW ECO:0000256|PIRNR:PIRNR037093};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892,
KW ECO:0000256|PIRNR:PIRNR037093};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034,
KW ECO:0000256|PIRNR:PIRNR037093};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037093};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR037093};
KW Reference proteome {ECO:0000313|Proteomes:UP000316621};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037093}.
FT DOMAIN 27..541
FT /note="Clathrin/coatomer adaptor adaptin-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01602"
FT DOMAIN 622..766
FT /note="Coatomer gamma subunit appendage Ig-like subdomain"
FT /evidence="ECO:0000259|Pfam:PF08752"
FT DOMAIN 769..883
FT /note="Coatomer subunit gamma C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16381"
FT REGION 593..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 886 AA; 98276 MW; ED92ACB08EEC63ED CRC64;
MAQPLIKKDD DRDDEAEYSP FLGIEKGAVL QEARVFHDPQ LDPRRCSQVI TKLLYLLNQG
ESFTKVEATE VFFAVTKLFQ SKDIGLRRMV YLIIKELSPS SDEVIIVTSS LMKDMNSKSD
MYRANAIRVL CRIIDGTLLT QIERYLKQAI VDKNPVVASA ALVSGIHLLQ TNPEIVKRWG
NEVQEAVQSR AALVQFHALA LLHQIRQNDR LAVSKLVTSL TKGTVRSPLA QCLLIRYTCQ
VIRETGVNTP TGDRPFYDYL EGCLRHKAEM VIFEAARAIT ELSGVTNREL TPAITVLQLF
LSSSKPVLRF AAVRTLNKVA MTHPLAVTNC NIDMESLISD QNRSIATLAI TTLLKTGNES
SVDRLMKQIT NFMSDIADEF KIVVVDAIRS LCLKFPLKYR SLMNFLSNIL REEGGFEYKK
AIVDSIVILI RDIPDAKESG LFHLCEFIED CEFTYLSTQI LHFLGDEGPK TSDPSKYIRY
IYNRVILENA TVRSSAVSTL AKYGALVESL KPRVFILLNR CLFDSDDEVR DRATLYLNTL
RGDGSEAETN SEAKEFLFGS LDVPLVNLEK SLKNYEPSEE AFDIDSVPKE VKSQPLAEKK
ATGKKQTGLG APPAGPKPVV DAYEKTLSSI PEFSSFGKLF KSSAPFELTE AETEYAVNVV
KHIFDDHVVF QYNCTNTIPE QQLENVTVIV DASEAEGFAK LAVKPLTALP YDSPGQTYVA
FEKPEGLAFG KFSNTLRFIV KEVDTSTGDV EDDGVEDEYQ LEDVEIVAAD YMLKIGVSNF
RNAWEGMGPE CEKVDEYGLG VRESLAEAVS AVISILGMQP CEGTEVVPSN SRSHTCLLSG
VFVGNVKVLV RLSFGIDGPK QVAMKLAVRS EDEAVSDAIH DIVASG
//
