ID A0A4Y9PT73_9MICO Unreviewed; 376 AA.
AC A0A4Y9PT73;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 28-JUN-2023, entry version 10.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:TFV82582.1};
DE EC=1.3.1.12 {ECO:0000313|EMBL:TFV82582.1};
GN ORFNames=E4V99_17035 {ECO:0000313|EMBL:TFV82582.1};
OS Microbacterium sp. dk485.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=2560021 {ECO:0000313|EMBL:TFV82582.1, ECO:0000313|Proteomes:UP000297593};
RN [1] {ECO:0000313|EMBL:TFV82582.1, ECO:0000313|Proteomes:UP000297593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=dk485 {ECO:0000313|Proteomes:UP000297593};
RA Dong K.;
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFV82582.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; SPQW01000002; TFV82582.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4Y9PT73; -.
DR OrthoDB; 9802008at2; -.
DR Proteomes; UP000297593; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:TFV82582.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000297593}.
FT DOMAIN 21..298
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 376 AA; 38926 MW; B70270080549C30D CRC64;
MSDSTNSSAR AAAPLAPRVR GTVRIVGAGL LGSSIGHALT ARGIDVALDD ASPAQLRLAV
DYGAGRMAQP DDAPSLIVVA VPPDVTADVI ARELSAHPGV VVTDVASVKL QPLHELRARG
IDLTHYIGSH PLAGRERGGA ISARADLFIG RPWVVCRDGE TPADDLALVE GLALDLGAVP
LEMSPEEHDR SVALVSHVPQ LVASLLAGRF VDAPDGALGL AGQGVRDTTR IAASAPELWV
QILGANAQPV VDVLDALAAD LSAVAAALRA PDAPGARRAV ADTIRRGNDG VERLPGKHGQ
NRRFDSFVVM IDDTPGQLGL LFGELGDLGV NVEDLRLEHS PGAQFGLAEI SVVPDAVRPA
TEGLTARGWR IASTND
//
