ID A0A4Z0YK01_9PEZI Unreviewed; 355 AA.
AC A0A4Z0YK01;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=Tyrosinase copper-binding domain-containing protein {ECO:0000259|PROSITE:PS00498};
GN ORFNames=E0Z10_g4575 {ECO:0000313|EMBL:TGJ84194.1};
OS Xylaria hypoxylon.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Xylariaceae; Xylaria.
OX NCBI_TaxID=37992 {ECO:0000313|EMBL:TGJ84194.1, ECO:0000313|Proteomes:UP000297716};
RN [1] {ECO:0000313|EMBL:TGJ84194.1, ECO:0000313|Proteomes:UP000297716}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 108379 {ECO:0000313|EMBL:TGJ84194.1,
RC ECO:0000313|Proteomes:UP000297716};
RA Buettner E., Leonhardt S., Gebauer A.M., Liers C., Hofrichter M.,
RA Kellner H.;
RT "Draft genome sequence of Xylaria hypoxylon DSM 108379, a ubiquitous
RT saprotrophic-parasitic fungi on hardwood.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC Evidence={ECO:0000256|ARBA:ARBA00001973};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TGJ84194.1}.
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DR EMBL; SKBN01000073; TGJ84194.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4Z0YK01; -.
DR STRING; 37992.A0A4Z0YK01; -.
DR Proteomes; UP000297716; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS00498; TYROSINASE_2; 1.
PE 4: Predicted;
KW Copper {ECO:0000256|ARBA:ARBA00023008}; Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000297716};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 280..291
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00498"
SQ SEQUENCE 355 AA; 40229 MW; D54DD0A7A0463A2D CRC64;
MPSSKYERED DQTSAEPLLE TTETGAQALS LRKRYVAATI AAIVFILVLL FLWALNGKTD
HSNSDGACRQ PAVRREWRTL SSLERLEYLR AVKCLSSIPS TVCNGTLHDE FSYIHRMIGD
YSHEAAPFLP WHRYFIHIYE KTLKQRCQYE GTLPYWDWTR DWADVTRAPV WDATEGLGGN
GNVNLPTSVG GGHCVQDGPF AGLQVQYYNE DWNPHCLSRG FLTGELLDHF GAQRLNTSAM
AAVLDQPDYY GFLLKLEDGP HSAIPIIVRG DFYRFTAPND PIFFLHHAQI DRLWFKWQSK
DLEMRALAYD GPSRHNSSIA AQLTDQLEMA GLAPDITVSS VMTINNGLLC YKFQD
//
