ID A0A4Z1TAR0_GIAMU Unreviewed; 1180 AA.
AC A0A4Z1TAR0;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Putative DNA-dependent ATPase {ECO:0000313|EMBL:TNJ29609.1};
GN ORFNames=GMRT_13997 {ECO:0000313|EMBL:TNJ29609.1};
OS Giardia muris.
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=5742 {ECO:0000313|EMBL:TNJ29609.1, ECO:0000313|Proteomes:UP000315496};
RN [1] {ECO:0000313|EMBL:TNJ29609.1, ECO:0000313|Proteomes:UP000315496}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Roberts-Thomson {ECO:0000313|EMBL:TNJ29609.1,
RC ECO:0000313|Proteomes:UP000315496};
RA Xu F., Jimenez-Gonzalez A., Einarsson E., Astvaldsson A., Peirasmaki D.,
RA Eckmann L., Andersson J.O., Svard S.G., Jerlstrom-Hultqvist J.;
RT "The compact genome of Giardia muris reveals important steps in the
RT evolution of intestinal protozoan parasites.";
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TNJ29609.1}.
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DR EMBL; VDLU01000001; TNJ29609.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4Z1TAR0; -.
DR VEuPathDB; GiardiaDB:GMRT_13997; -.
DR Proteomes; UP000315496; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015195; SLIDE.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR10799:SF879; CHROMATIN-REMODELING COMPLEX ATPASE CHAIN ISWI; 1.
DR PANTHER; PTHR10799; SNF2/RAD54 HELICASE FAMILY; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF09111; SLIDE; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000315496}.
FT DOMAIN 128..295
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 519..670
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 38..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1180 AA; 134236 MW; 0ECCA08E113AECBD CRC64;
MNLVRFRDKP LRQKLATVFG QTVLSDGGDT LQTVPSMRQL SKRSAGKGDE SDSDGPVATV
DKAPDLEVLS QPHCLTGGLL KEYQLESLQW LIGIHQTCTR FRLHFTDLPE NPRDLIPFSN
GRRAKLYSDI NAAQVGCILG DEMGLGKTIQ TISLLAFLHE HLDVRQPHLV IVPKSTLTQW
HDEFKKWAPC LKILVVIGDR ETREELIQQN FLDKGPLPDV CLTTYDVVRL ERKALSSVFW
YYMVLDEGHK LKDTESQISI ALRGYTTMHK LLLTGTPLQN NLHELWALLN FLSPLIFDKP
GEFVGLVKAT EEEAVQMSSS KSQPKLENTG GIEFRTTPVM SDESSSDEST TQTAITANTT
NTGTTGTATT NIKDTVSEKS PTTIGRKDVE PKMEGEMVPS TGEDGSVAAR MHDVLKLFLL
RREKKDVESL PQKHEYLINC GMTTLQRELY KGVLSKDLSS LNKVLRSTSE TSAVGKTSLV
NVIMQLRKCS DHPYLFPGVE PEPFKEGEHI INVSGKMVIM DKIIVRIKSI GEKVLVFCQM
TSMLNIIEDY LRFRGYAYCR IDGSTDLETR ARSMALFNNP ASEAFVFLLS TRAGCLGLNL
TAANHVIIYQ QDFNPQADLQ AVARAYRLLQ TKEVFVYRLI AENTVDTRIY ERAQVKLGLD
NLIIQSGNFT NSGQLNKLLG DTELRGRSMS RNQLLDMIAV SSESLFTIER TEEKHDYDIP
EITIDDAKLE ELLQNALRRR EDVSKRITQK VADASSILSQ LASDGKLEHV NTDQLYQFEG
QSYTKQSMRR IADLLQKEKD GKDEAERALR IANYSLMREE GDTAARKKDK RHFPTLRRLK
MAANVYKADI QLLAPEYYLL IGKIATEIST VIEPHMAEHP DLSYEDFATE RGYARPDLPG
LTPDELETLY SYLGTGCPYL DDNKEISRRE FNTLMGAFCD YEVEKYASMT GVRRLQYTPA
SRSTDGEQDT ESEHRRILAE LPAAPGFHFD KCYNIEVSGL ENMEIVYLVF AEKMRAGKES
ALRLTKQEIV RYCTALLENL DRIEDGAKIR QRIERARQRR RTYFKRVRIL RRWIDQYTDP
LYQLPIPSVT NQRRTFSDLQ DRFLLLMIDA CGLGCWHEVA TQIRLSPLFA MDWWFKTRTE
EELSKRADRL LKYIEQDIGD ISDSEGDAQL IQPRTRKSKI
//
