ID A0A4Z2DF99_SCHJA Unreviewed; 1018 AA.
AC A0A4Z2DF99;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Plasma membrane calcium-transporting ATPase 2 isoform 2 {ECO:0000313|EMBL:TNN15115.1};
DE Flags: Fragment;
GN ORFNames=EWB00_001608 {ECO:0000313|EMBL:TNN15115.1};
OS Schistosoma japonicum (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6182 {ECO:0000313|EMBL:TNN15115.1, ECO:0000313|Proteomes:UP000311919};
RN [1] {ECO:0000313|EMBL:TNN15115.1, ECO:0000313|Proteomes:UP000311919}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HuSjv2 {ECO:0000313|EMBL:TNN15115.1};
RC TISSUE=Worms {ECO:0000313|EMBL:TNN15115.1};
RA Hu W., Luo F., Yin M., Mo X., Sun C., Wu Q., Zhu B., Xiang M., Wang J.,
RA Wang Y., Zhang T., Xu B., Zheng H., Feng Z.;
RT "An improved genome assembly of the fluke Schistosoma japonicum.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TNN15115.1}.
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DR EMBL; SKCS01000155; TNN15115.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4Z2DF99; -.
DR Proteomes; UP000311919; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0005388; F:P-type calcium transporter activity; IEA:InterPro.
DR CDD; cd02081; P-type_ATPase_Ca_PMCA-like; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006408; P-type_ATPase_IIB.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01517; ATPase-IIB_Ca; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 3.
DR PANTHER; PTHR24093:SF369; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR24093; CATION TRANSPORTING ATPASE; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00122; E1-E2_ATPase; 2.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000311919};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 729..748
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 806..824
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 844..861
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 881..901
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 913..939
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 754..932
FT /note="Cation-transporting P-type ATPase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00689"
FT REGION 159..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..211
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:TNN15115.1"
SQ SEQUENCE 1018 AA; 112625 MW; 8A938AFE31980AE9 CRC64;
GQAPTFDESE GQAGWIEGLA ILIAVFVVVF VVALNDWQKE RQFRGLQNKI ESEHTFFVIR
KGDTKQISVK EIVVGDICQV KYGDLLPADG IVIQCNDLKI DESSLTGESD QVKKSETKDP
ILLSGTHVME GSGKMLVTAV GPNSQAGIIF ALLSSGAHEE HGGGNENKKD KKNKHKKVDK
KNKNSNTANA DTYQLKSKEN KNESCDPEHK SKPKKKPRRK EQSVLQSKLT KLAIQIGYVG
TCVAIATVLI LIIKFSVHTF AQNKEPWQTG KHLKQIVNYI ITGVTVLVVA VPEGLPLAVT
LSLAYSVKRM MKDNNLVRHL DACETMGNAT AICSDKTGTL TTNRMTAVQC FIGNKHYKRI
PTASELPESI INTIVMNISI NSGYTSKILP SDNPGGLPKQ VGNKTECALL GFVKSIGRSY
EEVRAQWSEE RLYKVYTFNS LRKSMSTVIK ESDNPLSFLL FTKGASEMVV KCCSWMMDEQ
SRPRPFSVQD QEHLTEAVIE PMAGEGLRTI GIAYKKITAA TNSRNPNDMI VQSEPNWDDE
EHLLEGLTLL GIIGIEDPVR PEVPAAIRQC QKAGITVRMV TGDNVNTARS IAMKCGIIQP
GENFLVIEGK EFNRRIRDKA TGKVRQDLFD QVWINLRVLA RSSPQDKYTL VGGIINSRAA
PSRQVVAVTG DGTNDGPALK RADVGFAMGI AGTDVAKEAS DIILTDDNFS SIVKAVMWGR
NVYDSITKFL QFQLTVNCVA IIVAFAGACF LDDSPLKAIQ MLWVNLIMDT LASLALATEQ
PSLELLDRAP YGRTQPLISR QMAKNILGHS LYQLSVIFFL LFYIDLIMEV DNVARITVHE
PTQHYTVIFN ALVLMTLFNE FNARKIHGQR NVFSGLHRNP LFVIIWFVTF LLQALIIQFG
SYAFSTKALE LDQWGWCLFF GVGELVWGQI VNTVPNAIIP KCKCRKRKHA TVVGTAENAA
VEFIKDSPDE TGEVYEDDEI SPLSLSGANM PLGGRILWLR GVNRIQTQMQ AVSALARK
//
