ID A0A4Z2EHV9_9TELE Unreviewed; 229 AA.
AC A0A4Z2EHV9;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Claudin-8 {ECO:0000313|EMBL:TNN28064.1};
GN Name=Cldn8_2 {ECO:0000313|EMBL:TNN28064.1};
GN ORFNames=EYF80_061790 {ECO:0000313|EMBL:TNN28064.1};
OS Liparis tanakae (Tanaka's snailfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Cottales; Liparidae; Liparis.
OX NCBI_TaxID=230148 {ECO:0000313|EMBL:TNN28064.1, ECO:0000313|Proteomes:UP000314294};
RN [1] {ECO:0000313|EMBL:TNN28064.1, ECO:0000313|Proteomes:UP000314294}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Muscle {ECO:0000313|EMBL:TNN28064.1};
RA Kim W., Song I., Jeong J.-H., Kim D., Kim S., Ryu S., Song J.Y., Lee S.K.;
RT "First draft genome of Liparis tanakae, snailfish: a comprehensive survey
RT of snailfish specific genes.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC {ECO:0000256|ARBA:ARBA00004435}.
CC -!- SIMILARITY: Belongs to the claudin family.
CC {ECO:0000256|ARBA:ARBA00008295}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TNN28064.1}.
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DR EMBL; SRLO01007348; TNN28064.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4Z2EHV9; -.
DR Proteomes; UP000314294; Unassembled WGS sequence.
DR GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR006187; Claudin.
DR InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR PANTHER; PTHR12002; CLAUDIN; 1.
DR PANTHER; PTHR12002:SF41; CLAUDIN-6; 1.
DR Pfam; PF00822; PMP22_Claudin; 1.
DR PRINTS; PR01077; CLAUDIN.
PE 3: Inferred from homology;
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000314294};
KW Tight junction {ECO:0000256|ARBA:ARBA00022427};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 79..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 206..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 229 AA; 24845 MW; 32C462C06E52D4CE CRC64;
MVNTSMQLIS FTCAVTGWIM AIAVTALPQW KVSAFIGSNI LTSEIKWEGI WMNCIYQTTG
HMQCKTYDSM LALPPDIQAA RALMCVAIFM GWLSCTVSCC GMKCTTCAGD DRRAKAGIAL
SGGVLFILTG LCVLIPVSWT ANTVVQDFYN PKVPLMHKRE LGQAVYLGWA SAVILMISGA
VLSSTCPLVE RSGRYRRGYV GRSFANTPAS APEPPRPITS NSVPLKEYV
//
