ID A0A504IUQ3_9FLAO Unreviewed; 1183 AA.
AC A0A504IUQ3;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=NAD(P)H-nitrite reductase {ECO:0000313|EMBL:TPN82207.1};
GN ORFNames=FHK87_22545 {ECO:0000313|EMBL:TPN82207.1};
OS Aquimarina algicola.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Aquimarina.
OX NCBI_TaxID=2589995 {ECO:0000313|EMBL:TPN82207.1, ECO:0000313|Proteomes:UP000315540};
RN [1] {ECO:0000313|EMBL:TPN82207.1, ECO:0000313|Proteomes:UP000315540}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M625 {ECO:0000313|EMBL:TPN82207.1,
RC ECO:0000313|Proteomes:UP000315540};
RA Meng X.;
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TPN82207.1}.
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DR EMBL; VFWZ01000009; TPN82207.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A504IUQ3; -.
DR OrthoDB; 9792592at2; -.
DR Proteomes; UP000315540; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd02791; MopB_CT_Nitrate-R-NapA-like; 1.
DR CDD; cd02754; MopB_Nitrate-R-NapA-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.30.390.30; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR007419; BFD-like_2Fe2S-bd_dom.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR041957; CT_Nitrate-R-NapA-like.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR041575; Rubredoxin_C.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04324; Fer2_BFD; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF18267; Rubredoxin_C; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000315540}.
FT DOMAIN 4..60
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 1183 AA; 132916 MW; DFBA3B65E0582DFC CRC64;
MSAFKTYKTT CSYCGVGCGI IAKKDRRGVI TVEGDPDHPV NRGMLCSKGM NLHHVVQDKE
DRILYPEMRW SKEHARERVS WDQALDRAAK VFNTIIKKHG PDSVGFYVSG QCLTEEYYLV
NKLTKGFIGT NNLDTNSRLC MSSAVVGYKQ AFGEDSVPIS YDDIELADCF MIAGANPAWC
HPILYRRIEA RKEKNPSTKI IVVDPRKTQS CDIADLHLQI LPGTDVALYN AIAKRLIDRK
KIDKSFIHGH TDNFNALKES VCSFSLTEYA KICGITVAEI KKAASYISNA KGFITLWAMG
LNQSSIGVNK NNALINLSLL TGHIGKPGSG PFSLTGQPNA MGGREVGGMA NLLAAHKDLA
NDHHRREVAN FWGGKEISSK PGLTATEMFD ALENGKLKAV WIICTNPLVS LPNANKVEKA
LKNAKFVVVQ DISNRSETIE HADLVLPAAG WAEKEGTMTN SERRITYLDK VVDPPGEALP
DVEILWRFAR KMGYKGFDYN SAEEVYKEHC SLTKGTNIDI SGLNYIRLKT EGSFQWPVPK
NNHAGTERLF EDKKFYTDTG NAKFVVPKFI KPTSEICTEK YPLILTSGRI RDQWHTRTKT
GKVNRLLTHI RDPYIEVNQV DAFLRKLNDG DIAIVESKRG KVRVRVKVCD TLNKGVVFMP
IHWGKVFGND YGRVNNLTTN IVDPMSKEPD FKFSAVQVSK YVKSKQKICV IGAGTAAYRF
IQTYREYNTD DEIVVFSKES HPFYNRVLLP EYVSEELKWE QLQKMREGSM ESLDVKLYTD
NPINEINREE KYIIDSKGVQ HDYDVILMAT GSRAFIPKEV PLHLPGRFTM RDRGDADRLK
TYLDQTGLPD HHQHVTIVGG GLLGLELAAA LRKKKVKITI VQRGNRLMER QLDEVASQLL
AEDVREKGII IHFDNEVDTV LNQETGELLV NLKSGKSFQC HAVVYAIGTI PNIDLAKKVD
IDCRRGILVN QYMQSCDKDI FAIGEIAEFN GNLYGITAAA EQQADIVAKY LLGDFSAIYR
GSVFMNILKF EDLDLCSIGN IDMPKNDLSY EEVVFTDVRK RFYKRCIIKN DRLVGAILMG
DKSEFAEFKR YIEEKIELSE KREELLRSSR SSEPVIGKLI CSCSQVGEGN LQKAIKSGCT
DFSELCNRTG AGLGCGSCKP EVKEILNNYE QRGNEKRTKI IQN
//
