ID A0A507ASH0_9PEZI Unreviewed; 1207 AA.
AC A0A507ASH0;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 13-SEP-2023, entry version 15.
DE RecName: Full=Urea carboxylase {ECO:0008006|Google:ProtNLM};
GN ORFNames=E0L32_006587 {ECO:0000313|EMBL:TPX12942.1};
OS Thyridium curvatum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetes incertae sedis; Thyridiaceae; Thyridium.
OX NCBI_TaxID=1093900 {ECO:0000313|EMBL:TPX12942.1, ECO:0000313|Proteomes:UP000319257};
RN [1] {ECO:0000313|EMBL:TPX12942.1, ECO:0000313|Proteomes:UP000319257}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D216 {ECO:0000313|EMBL:TPX12942.1,
RC ECO:0000313|Proteomes:UP000319257};
RA Varaljay V.A., Lyon W.J., Crouch A.L., Drake C.E., Hollomon J.M.,
RA Nadeau L.J., Nunn H.S., Stevenson B.S., Bojanowski C.L.,
RA Crookes-Goodson W.J.;
RT "Draft genome sequence of the filamentous fungus Phialemoniopsis curvata
RT isolated from diesel fuel.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=biotin; Xref=ChEBI:CHEBI:57586;
CC Evidence={ECO:0000256|ARBA:ARBA00001953};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TPX12942.1}.
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DR EMBL; SKBQ01000038; TPX12942.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A507ASH0; -.
DR STRING; 1093900.A0A507ASH0; -.
DR InParanoid; A0A507ASH0; -.
DR OrthoDB; 313213at2759; -.
DR Proteomes; UP000319257; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.30.1360.40; -; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 2.40.100.10; Cyclophilin-like; 2.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR005481; BC-like_N.
DR InterPro; IPR001882; Biotin_BS.
DR InterPro; IPR011764; Biotin_carboxylation_dom.
DR InterPro; IPR005482; Biotin_COase_C.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR InterPro; IPR003778; CT_A_B.
DR InterPro; IPR003833; CT_C_D.
DR InterPro; IPR029000; Cyclophilin-like_dom_sf.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR011054; Rudment_hybrid_motif.
DR InterPro; IPR011053; Single_hybrid_motif.
DR NCBIfam; TIGR00724; urea_amlyse_rel; 1.
DR PANTHER; PTHR18866; CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE; 1.
DR PANTHER; PTHR18866:SF33; METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF02785; Biotin_carb_C; 1.
DR Pfam; PF00289; Biotin_carb_N; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF02786; CPSase_L_D2; 1.
DR Pfam; PF02626; CT_A_B; 1.
DR Pfam; PF02682; CT_C_D; 1.
DR SMART; SM00796; AHS1; 1.
DR SMART; SM00797; AHS2; 1.
DR SMART; SM00878; Biotin_carb_C; 1.
DR SUPFAM; SSF50891; Cyclophilin-like; 2.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF160467; PH0987 N-terminal domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR SUPFAM; SSF51246; Rudiment single hybrid motif; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS50979; BC; 1.
DR PROSITE; PS00188; BIOTIN; 1.
DR PROSITE; PS00866; CPSASE_1; 1.
DR PROSITE; PS00867; CPSASE_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Biotin {ECO:0000256|ARBA:ARBA00023267};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Reference proteome {ECO:0000313|Proteomes:UP000319257}.
FT DOMAIN 2..443
FT /note="Biotin carboxylation"
FT /evidence="ECO:0000259|PROSITE:PS50979"
FT DOMAIN 115..314
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT COILED 1096..1123
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1207 AA; 131874 MW; 35DE9832D07B7303 CRC64;
MEIKRLLIAN RGEIAYRILR TAKRLGYFVV AIYTQTDVSS PHVLDADLPC LVKSYVDIDE
IVAIVRQQAI HLVIPGYGFL SENEAFAAAV VKAGAAFVGP DPEHIAAFGI KHRARDLAEK
VGVPICPGSG ILNSEDEAVL AATKIGYPVM LKATAGGGGM GLQICENEAE VRSSFTSVVS
RGSTLFSNPG VFLERYYAVS RHVEVQIFGD GQGRCVVFGE RECSIQRRHQ KVIEESPSPF
VEMRPALRKR LFEVSELLGQ SIKYRSAGTI EFLVDDATAD FFFLEMNTRL QVEHGITELR
FDIDLVELML RLAEGTLNIS EYMLLEPRGT AIEARVYAEN PLKNHMPSPG VLQHAYFAEG
PGVRVDTWVR TGTNVSLAYD PLLAKVMGYG ATREEATTTI VGALRDTKLQ GIVTNLSLLF
RILTSQDFRD GNTTTGFLTD FDHTPRSMEI LTAGSYTTIQ SWPGRVGVGF GIPEGGPMDP
LHAQLANCIV GNDRGCELLE ITFTGPKIRF HSRAIVCLTG AGAHGMELDG VPIPMCTSLE
APAGSVLAVG SLSGGSRAYL AIRGGLPSIP YYLGSKATSP VADIGGLQGR ALVAGDLLEL
PEAGSFRAFS LPSSLIPEWD PHVIHCLSGP HDSPDIILSE ALPALCESEW TVSHQASRVG
IRLHGPQPQW ARTTGGEGGS HPSNYLDYPY SIGALNWTGD SAVIFPADAP SLGGFISSHV
VARAEMFKVA QLRPGDKFRL SPISVDAAMD LRRRQEAFLE TIRKLVASGN STFSAISPLS
LAVPNSLSCS KSTAILERCE DITIRQAGDS YILVEFHQSL DLDTRCRVQS VLEAIEEAHI
NGVRLATPIG CSLLIDYEGF EISQMELVLK VKDILVAQFA TQISQSTMLN SRLIKLPMVF
DDKVNKAAIE RYMATQRKYA SYLPDPVEFI ARSNGLDSKD DVRKKVLNTR ILVVGVGFFN
GTPIGIPLDP RSRLIVPKFN PSRTFSPEGG LGFGGSFFTC DPIDAPGGYV NFGRTLPGWD
KYCLNKDFGQ RPWLFNNFDQ LEFYEVTEDE LDKIYARFKA GRFDFDISPA TFDVEAYSRF
CESVAVETQT FKAKQQLATE REIERENKLL AQWQEDQNGE KDEVQGLDDI DDSLKVQAET
HASVYKIPAQ KGTKVKAGDV LLVLEAMKME INLLASAEHE GSVIRSIVVG PNDVVKPGDT
LIVLAQA
//
