ID A0A507F691_9FUNG Unreviewed; 590 AA.
AC A0A507F691;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=Tyrosinase copper-binding domain-containing protein {ECO:0000259|PROSITE:PS00498};
GN ORFNames=CcCBS67573_g06102 {ECO:0000313|EMBL:TPX71632.1};
OS Chytriomyces confervae.
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Chytridiales;
OC Chytriomycetaceae; Chytriomyces.
OX NCBI_TaxID=246404 {ECO:0000313|EMBL:TPX71632.1, ECO:0000313|Proteomes:UP000320333};
RN [1] {ECO:0000313|EMBL:TPX71632.1, ECO:0000313|Proteomes:UP000320333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 675.73 {ECO:0000313|EMBL:TPX71632.1,
RC ECO:0000313|Proteomes:UP000320333};
RX PubMed=31209237; DOI=.1038/s41598-019-45128-9;
RA van de Vossenberg B.T.L.H., Warris S., Nguyen H.D.T.,
RA van Gent-Pelzer M.P.E., Joly D.L., van de Geest H.C., Bonants P.J.M.,
RA Smith D.S., Levesque C.A., van der Lee T.A.J.;
RT "Comparative genomics of chytrid fungi reveal insights into the obligate
RT biotrophic and pathogenic lifestyle of Synchytrium endobioticum.";
RL Sci. Rep. 9:8672-8672(2019).
CC -!- COFACTOR:
CC Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC Evidence={ECO:0000256|ARBA:ARBA00001973};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TPX71632.1}.
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DR EMBL; QEAP01000245; TPX71632.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A507F691; -.
DR STRING; 246404.A0A507F691; -.
DR Proteomes; UP000320333; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS00498; TYROSINASE_2; 1.
PE 4: Predicted;
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000320333};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..590
FT /note="Tyrosinase copper-binding domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5021418032"
FT DOMAIN 257..268
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00498"
SQ SEQUENCE 590 AA; 63715 MW; 9990A4C2C1FBDA43 CRC64;
MKLLALLVVA GHALAQCTNP RVRQEWNTLS SSDKAAFVAA CAALAKRPLS NQYADPSIMS
WHDFVVTHSE NAFWSHVRAV RCDSTTITKP AVALQGNAQF YPYHRAMVWQ FEKAIISTGL
WPASKGIPYW DWSAVSQNWW TSDVFSPSYF GSASSSDPDI CVVDGAFAKG VYSVAPDALK
NRKITTGDLT CLRRNGGQYV LPDATSMQDA LSASSYLQFT CQDPNTYYDL SNYHASGHGT
IGGPGSDLAD ASVSPNDPIF WLHHGFVDKY WFRWQSQCPQ FKFDYTGVLK RQDATGLTDS
SPYANLDSWP FTVQQMMDVQ GDTLCYTYGP SKGDLPASSP PACPAVKPLA AQTGTASSSA
STTGTAKSGV DDIWLRSMFV KLVKTPSLGS FNAGTSAAGS AGIDAAGGGD SGAIIIMGRD
NTTDQDAGAG TVAVSATGTV PATQTATVVA TSSAVASEEA VSKVDEGYIE TQLPDGSTLV
SYTHFNHTVQ IPATHEVFLV FSRSVAAIDK KTYKKKRFFS PLEPQEYSQP ANYTDLSNEP
GRCWLKYPQR VPESYLAGMN MDVAMYNNVY NLQMMAIDKF NMESGTSPSC
//
