ID   A0A509AJC5_PLABA        Unreviewed;       888 AA.
AC   A0A509AJC5;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Arginine--tRNA ligase, putative {ECO:0000313|EMBL:VUC55308.1};
GN   ORFNames=PBANKA_0814900 {ECO:0000313|EMBL:VUC55308.1};
OS   Plasmodium berghei (strain Anka).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Vinckeia).
OX   NCBI_TaxID=5823 {ECO:0000313|EMBL:VUC55308.1, ECO:0000313|Proteomes:UP000074855};
RN   [1] {ECO:0000313|EMBL:VUC55308.1, ECO:0000313|Proteomes:UP000074855}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ANKA {ECO:0000313|EMBL:VUC55308.1,
RC   ECO:0000313|Proteomes:UP000074855};
RX   PubMed=25359557; DOI=10.1186/preaccept-1233682211145405;
RA   Otto T.D., Bohme U., Jackson A.P., Hunt M., Franke-Fayard B.,
RA   Hoeijmakers W.A., Religa A.A., Robertson L., Sanders M., Ogun S.A.,
RA   Cunningham D., Erhart A., Billker O., Khan S.M., Stunnenberg H.G.,
RA   Langhorne J., Holder A.A., Waters A.P., Newbold C.I., Pain A., Berriman M.,
RA   Janse C.J.;
RT   "A comprehensive evaluation of rodent malaria parasite genomes and gene
RT   expression.";
RL   BMC Biol. 12:86-86(2014).
CC   -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|ARBA:ARBA00005594, ECO:0000256|RuleBase:RU363038}.
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DR   EMBL; LK023123; VUC55308.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A509AJC5; -.
DR   STRING; 5823.A0A509AJC5; -.
DR   VEuPathDB; PlasmoDB:PBANKA_0814900; -.
DR   InParanoid; A0A509AJC5; -.
DR   OrthoDB; 241454at2759; -.
DR   Proteomes; UP000074855; Chromosome 8.
DR   GO; GO:0004814; F:arginine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006420; P:arginyl-tRNA aminoacylation; IEA:InterPro.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR001278; Arg-tRNA-ligase.
DR   InterPro; IPR035684; ArgRS_core.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR11956:SF5; ARGININE--TRNA LIGASE, CYTOPLASMIC-RELATED; 1.
DR   PANTHER; PTHR11956; ARGINYL-TRNA SYNTHETASE; 1.
DR   Pfam; PF00750; tRNA-synt_1d; 2.
DR   PRINTS; PR01038; TRNASYNTHARG.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|RuleBase:RU363038};
KW   ATP-binding {ECO:0000256|RuleBase:RU363038};
KW   Ligase {ECO:0000256|RuleBase:RU363038, ECO:0000313|EMBL:VUC55308.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU363038};
KW   Protein biosynthesis {ECO:0000256|RuleBase:RU363038};
KW   Reference proteome {ECO:0000313|Proteomes:UP000074855};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..888
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5021199146"
FT   DOMAIN          209..356
FT                   /note="Arginyl-tRNA synthetase catalytic core"
FT                   /evidence="ECO:0000259|Pfam:PF00750"
FT   DOMAIN          511..620
FT                   /note="Arginyl-tRNA synthetase catalytic core"
FT                   /evidence="ECO:0000259|Pfam:PF00750"
SQ   SEQUENCE   888 AA;  107144 MW;  47E9A14E92B5333A CRC64;
     MNRWVFMVWV FFFFLEEFKF KQMSHILNDC SYLYNQIKKK TRYINAYLER NKIISLKKGK
     SKQKKINSLN THLHSSLYSN PHNDIKKEVQ IYEILNNAIK NVVKKVIKNE NLLIPKQYLL
     EYNKLYDDYE YQSGIIMFID KDIRDGVSIN GSENEHKHFR QKIIESLKNE CSDIIDDIRL
     SQNGILNIRV KDEYIKRRFY EFHTQLNENK QNDQIKTDEK KNVVVLDYCG VNMAKHMHVG
     HLKSLFLGYA LNNIFDYFNF NVKSRNHIGN WNSNIAMVIT FFIFFLSENW CNQFVINSSS
     LLQNSENIKT NNNCFSDIFV EKNENFQIVK KYLDILNNLK ENNFYDNYEK FNINKIENIN
     LDNIDNAYKI SKELYSINTL FQKCTKHILS LMYKYDDKTI QLWNVLCDKT RKENDEILRI
     FKIHKLIEKG EDFYVKYVPK VLEEMEKKKI LFKFGNKLCV LFKKKKNLEI EKTKINCNDK
     DYYEVVQVQD KIYDDLKNGD INILKKNYHI LTLKNDIAYT YAGIDLASIY YRVYFEKADK
     IIYVVDENQK NHFMQIFSIY KNMNMFSKDV EYKCICYGFV LNNEKKKIKT KNFTNNTFVK
     DVIQNLQQIE EKKIKKNDEN EYNENCYDDN NEGKFIYNKR YYTKKNYKNL LLSSIVYSYI
     SVKNCKRQTI NNLINSYNFE YIYIINNYND IYFILGNLKK SDYSFIYEEK YYINMDYRLK
     KLLLDIMNFK NILKNVIYNY NVDKLCSYLF SLSQKTHHFA RDSFNKNFLH NFEEKNIHKF
     LNFIKNISKE KIANTIINLE KKKYDIFDDE KITYLNLFIN FIKSDKDHNP TINKINSFSK
     DELNKIMSFF LNKTFEIIVM QSYLFIVSEI FDILNLYLVK FDTPEIIK
//