ID   A0A509ASH0_PLABA        Unreviewed;       695 AA.
AC   A0A509ASH0;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=AMP deaminase {ECO:0000256|ARBA:ARBA00012775};
DE            EC=3.5.4.6 {ECO:0000256|ARBA:ARBA00012775};
GN   ORFNames=PBANKA_1344400 {ECO:0000313|EMBL:VUC57831.1};
OS   Plasmodium berghei (strain Anka).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Vinckeia).
OX   NCBI_TaxID=5823 {ECO:0000313|EMBL:VUC57831.1, ECO:0000313|Proteomes:UP000074855};
RN   [1] {ECO:0000313|EMBL:VUC57831.1, ECO:0000313|Proteomes:UP000074855}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ANKA {ECO:0000313|EMBL:VUC57831.1,
RC   ECO:0000313|Proteomes:UP000074855};
RX   PubMed=25359557; DOI=10.1186/preaccept-1233682211145405;
RA   Otto T.D., Bohme U., Jackson A.P., Hunt M., Franke-Fayard B.,
RA   Hoeijmakers W.A., Religa A.A., Robertson L., Sanders M., Ogun S.A.,
RA   Cunningham D., Erhart A., Billker O., Khan S.M., Stunnenberg H.G.,
RA   Langhorne J., Holder A.A., Waters A.P., Newbold C.I., Pain A., Berriman M.,
RA   Janse C.J.;
RT   "A comprehensive evaluation of rodent malaria parasite genomes and gene
RT   expression.";
RL   BMC Biol. 12:86-86(2014).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via salvage pathway; IMP
CC       from AMP: step 1/1. {ECO:0000256|ARBA:ARBA00004955}.
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
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DR   EMBL; LK023128; VUC57831.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A509ASH0; -.
DR   STRING; 5823.A0A509ASH0; -.
DR   VEuPathDB; PlasmoDB:PBANKA_1344400; -.
DR   InParanoid; A0A509ASH0; -.
DR   OMA; FHRKFPY; -.
DR   OrthoDB; 20951at2759; -.
DR   UniPathway; UPA00591; UER00663.
DR   Proteomes; UP000074855; Chromosome 13.
DR   GO; GO:0003876; F:AMP deaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032264; P:IMP salvage; IEA:UniProtKB-UniPathway.
DR   Gene3D; 4.10.800.20; -; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR006650; A/AMP_deam_AS.
DR   InterPro; IPR006329; AMPD.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   NCBIfam; TIGR01429; AMP_deaminase; 1.
DR   PANTHER; PTHR11359; AMP DEAMINASE; 1.
DR   PANTHER; PTHR11359:SF0; AMP DEAMINASE; 1.
DR   Pfam; PF19326; AMP_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
DR   PROSITE; PS00485; A_DEAMINASE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000074855}.
SQ   SEQUENCE   695 AA;  81242 MW;  C49833245C34ABAB CRC64;
     MNDQKNEGNI PDYSNNSKEG WSLFHEKIIE STRGSIQYDE TQLIDNSVID LKSSNRFSFT
     ISSTGIVSPE ESEVAKKILK ICNLRDIFMK EYPDIDTTLI RSNTLSEADK EKDTDHLKSS
     EPLYDLKNAL ILKKCNAFIN CVEGIFFVHW DPDSDVGPQK AEECNENNKI KGHNEIKTTE
     EYLEAIQEIM TTAQDPACKS FCYQRLKYLE QKFDFHIMFN GPLELKETAN IKHRDFYNIR
     KVDAHVHHSA CMQQKSLLRF IREKYNTEPD TIVYVNENGK KIKLKELFDD ELKFSAHQAT
     VDNLDVHALG NCFHRFDLFN EKYNPFGQKL LRDIFLKTDN YIEGKYLAEI TKQEINILEK
     SKYQHVEWRI SIYGKDKNEW SKLAKWVLNN NLTSVRVRWI IQIPRLYHIY KKRKLIHSFQ
     DFLSNIFEPC FEAIKNPEQN KDIFLFLKQI VGWDSVDDES IISKYTLKGG VLPSPDKYIS
     DNNPPYSYYA YYMYANIRTL NDFMIARKLR PLTFRPHCGE IGNISHLASM FLLANRINHG
     IALRKSPVLL YLYYLKQIGL AMSPLSNNAL FLSIEKNPFK QFFKIGLNVS LSTDDPLMFH
     FTSEPLLEEY SVCAHVWRLT TMDLCEIARN SIIQSGYEPS FKRHWLGKGG ENSSPNFTST
     PEKTNIPKTR MSYRKKTWNE ENENIIRLAN YFNKS
//