ID A0A509ASM2_PLABA Unreviewed; 530 AA.
AC A0A509ASM2;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Translation initiation factor eIF2B subunit beta {ECO:0000256|ARBA:ARBA00044122};
DE AltName: Full=eIF2B GDP-GTP exchange factor subunit beta {ECO:0000256|ARBA:ARBA00044228};
GN ORFNames=PBANKA_1463500 {ECO:0000313|EMBL:VUC58699.1};
OS Plasmodium berghei (strain Anka).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Vinckeia).
OX NCBI_TaxID=5823 {ECO:0000313|EMBL:VUC58699.1, ECO:0000313|Proteomes:UP000074855};
RN [1] {ECO:0000313|EMBL:VUC58699.1, ECO:0000313|Proteomes:UP000074855}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ANKA {ECO:0000313|EMBL:VUC58699.1,
RC ECO:0000313|Proteomes:UP000074855};
RX PubMed=25359557; DOI=10.1186/preaccept-1233682211145405;
RA Otto T.D., Bohme U., Jackson A.P., Hunt M., Franke-Fayard B.,
RA Hoeijmakers W.A., Religa A.A., Robertson L., Sanders M., Ogun S.A.,
RA Cunningham D., Erhart A., Billker O., Khan S.M., Stunnenberg H.G.,
RA Langhorne J., Holder A.A., Waters A.P., Newbold C.I., Pain A., Berriman M.,
RA Janse C.J.;
RT "A comprehensive evaluation of rodent malaria parasite genomes and gene
RT expression.";
RL BMC Biol. 12:86-86(2014).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
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DR EMBL; LK023129; VUC58699.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A509ASM2; -.
DR STRING; 5823.A0A509ASM2; -.
DR VEuPathDB; PlasmoDB:PBANKA_1463500; -.
DR InParanoid; A0A509ASM2; -.
DR OMA; SHSCAVA; -.
DR OrthoDB; 197125at2759; -.
DR Proteomes; UP000074855; Chromosome 14.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR45859; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA; 1.
DR PANTHER; PTHR45859:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA; 1.
DR Pfam; PF01008; IF-2B; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Initiation factor {ECO:0000313|EMBL:VUC58699.1};
KW Protein biosynthesis {ECO:0000313|EMBL:VUC58699.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000074855}.
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 48..79
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 530 AA; 61605 MW; 67FB91CA184669C0 CRC64;
MISQDTDIKN NSYYQNDDKQ KNKMKEAHAN NNILDKNENK LYAPNNNIHN LSKNNDNIIN
NITNEKKNMN NNLENNKSTN EIQLNNNYNK CYKDEYIEQN KKMHTNKYDS KDISLHNQNI
CNTNFKENEI IKFEKKQKKS EKLKKNRQKE IISAYWLKGI ADILNEGFKN GYIKGSNIIG
KKIADVLKKV VEIYHWESVY ELIEIIKYLG KEIIKNNKMI FIIPNIIRRV LTIIRTEHFK
QLYLYNNNYI DIMNKNNNMI IDELTNKTVN NNFLYERELL NFEKSLSSYF ENSSKRNTYK
ISATNTLKHS IIEGITELIA EIDLSWGETE QRTSYDLFME NDVILTMGYS FGVEKFLKNI
NKKKEGISII VVGGDINRNG FKMAKLLSED GVDTTYIPDS AIYAVIPKVT KVVIGSVAVS
SSGGAITKIG GYNIACSAFF YSKPVIVVLP LFKLLYDPLY DPLRQNELQP GPPMIYDNTE
NLYIRISKYD YIPQKYINLY ITEIGPIDSF QLYNIAKKKY HPDDIDLSFD
//
