ID A0A510TFC3_9ACTN Unreviewed; 451 AA.
AC A0A510TFC3;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN ORFNames=TNCT1_32230 {ECO:0000313|EMBL:GEK00947.1};
OS Streptomyces sp. 1-11.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2590549 {ECO:0000313|EMBL:GEK00947.1, ECO:0000313|Proteomes:UP000317474};
RN [1] {ECO:0000313|EMBL:GEK00947.1, ECO:0000313|Proteomes:UP000317474}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1-11 {ECO:0000313|EMBL:GEK00947.1,
RC ECO:0000313|Proteomes:UP000317474};
RA Oshiki M., Saito N.;
RT "Draft genome sequencing of Streptomyces sp. 1-11.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:83421; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001512};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001482};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GEK00947.1}.
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DR EMBL; BJTV01000006; GEK00947.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A510TFC3; -.
DR OrthoDB; 9801841at2; -.
DR Proteomes; UP000317474; Unassembled WGS sequence.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR47992:SF267; ALPHABET, ISOFORM E; 1.
DR PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR Pfam; PF13672; PP2C_2; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000317474}.
FT DOMAIN 185..441
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT REGION 41..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 451 AA; 46145 MW; 49F2C0A3BE2107E7 CRC64;
MSQMPQQTAL AKCPSCAEPL EPGDLFCGAC GYDLSVVPAP PQDHPTLTMT AGAGPGDGVD
WPAPEPDGSG STQPAAHRAA DLPGTDSGGN ALPHDPHQEP ATPGVRFDRR PEPEEYPLQA
PDPRAATSPA ASPAPDGPAA APGPADPAQV CVACRTGRVD DDGYCENCGH AQPRERDHME
RESGLVAAVS DRGLRHHRNE DAFAVAHTAL PDGSPAALAI VCDGVSSATR PDEASAAASQ
AAVDTLLAVL PRGTNPQAAM HEAIVAAAQA VDSLAGEPDA AREHDPHHNA PACTIVGAIV
TGGLLVVGWV GDSRAYWVPD DRSAPPARLT EDDSWAAQMV AAGLMSEAQA YADERAHAIT
GWLGADAYEL EPHTAAFKPD RPGVVLVCTD GLWNYAETAG EMAEVAPADA AARPLHCARV
LVGHALDGGG HDNVTVAVLP FPAPPQGAGS A
//
