ID A0A512UC19_9ASCO Unreviewed; 1305 AA.
AC A0A512UC19;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GEQ68609.1};
GN ORFNames=JCM33374_g2277 {ECO:0000313|EMBL:GEQ68609.1};
OS Metschnikowia sp. JCM 33374.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowia.
OX NCBI_TaxID=2562755 {ECO:0000313|EMBL:GEQ68609.1, ECO:0000313|Proteomes:UP000319698};
RN [1] {ECO:0000313|EMBL:GEQ68609.1, ECO:0000313|Proteomes:UP000319698}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 33374 {ECO:0000313|EMBL:GEQ68609.1,
RC ECO:0000313|Proteomes:UP000319698};
RA Hirao A.S., Imai R., Endoh R., Ohkuma M., Degawa Y.;
RT "Draft genome sequence of a novel Metschnikowia sp. strain JCM 33374, a
RT nectar yeast isolated from a bumblebee.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GEQ68609.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BIMT01000017; GEQ68609.1; -; Genomic_DNA.
DR STRING; 2562755.A0A512UC19; -.
DR Proteomes; UP000319698; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR PANTHER; PTHR11827:SF72; GH08340P; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000319698};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 39..526
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 538..636
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 937..1073
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 938..962
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 983..1010
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1305 AA; 143212 MW; 5369BABBFCE06E29 CRC64;
MSDTSPLLPK TRRQGKTKKG AAAAAAAAAK SKLGTFDGVF LPTSLNVLSI LMFLRFGFIV
GQMGIMGSVL LLVMSYLINV LTVLSISAIS TNGTVKGGGA YYMISRSLGP EFGGAIGVIF
FIGQILNASL NVVGFIEPLL VNFGKVDGDI LPLLPVSHWW EMVYSTILLA LCTAVAIVGS
SLVSKTAFWL FVLLTLSTLS IPASALFMPA GFPIPPPLEH LKYTGLSWAT TVENLWPHFT
SGAVGSVQPP GVPETFRNMF GIFFPATAGI FAGASMSGDL ANPSRSIPKG TLYGLLTSFI
LYLLVIVSLG ASTPRELLHK DIKIIQSVNM NGLIIIIGEV STSLFSVIMG VVGAASMLNA
IADDRIIPGL SLFATRKKSP SQKRRAELYS IFLTWVLAQV FLFADINQIA TFITMAFLMT
FLVTNLACFL LRLGSAPNFR PSFKYFNSKT AFTGGLTSII AMYICDGVSA TSVIIFLVFL
IMVIHYSTPP SKFGDISQLL IYHQVRKYLL RLKLQMSVKY WRPQILLLCD DPQTSWNLIG
FCNHLKKGGL YILGHVVLLT DEGAKNTSTN VSSEFNVDSF KEVQKQKNAW VKLRDMAKIK
AFVQIAIGPS LPWGVRNVFL GSGLGGMKPN ITVIGFYDFQ KHGVELPMKQ AHLQLPTDDC
RKEKKVSVNQ WVQIVEDLVI MQATVAVAAN FRGLSLPVFD KSWIKNKMAQ REPKAKKYID
LYPIQMSTIC LLEDGKSVMS TNFDTYTLIL QLGSILSTVD EWEQNGYVLR IIAFVESSSE
QEDEKQRLEN LLSSLRIDAE VKIVCFDSEN LHSYNLMVKG CDVTDETSEI FEHIESILEE
DQWWINMVEA REAIRDVESQ KQQKKSTGSI SRAIKIADDL PERLRSLNFS PKSPSEGLGL
GKSLQNNRRY TLSTLHQQGL SMSLNMKAQG DGSFFKYDDT IDTTDESDTE KEYIKEDTAS
HRSSVLHQQG IIPPPANPAG PTYGAAQRSS PSPTCQPQEN VSSAASRARS SAIGQGAKRR
TKLHSRSPDR LSLRASKSNL RPNFSAGKIP HSKIRDDEDD GEVDEESEDV KPSIAFVEEG
DESGDEENEA SEAVDANVVN VDGITAGDKL VKENVSTNNS SNNSLMEKSN AGLKETSRRA
IQGKKIGQTV HFNPKFEDRG KTSTPSILTN DGIHEHLQSP RFRDEDEDIS ASSREVSTLN
LLGNATAAEP ENKLTHKQLQ KELEQLTFSD LPAKGQHIIL NELMKKISKK DETAVIFSTL
PAPAIGTHLD DDESAAYTNS LAIWLDDLAP VLLLNSQTVT VTTSL
//
