ID A0A516KBK9_9BACI Unreviewed; 226 AA.
AC A0A516KBK9;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Deoxynucleoside kinase {ECO:0000313|EMBL:QDP38783.1};
GN ORFNames=FN924_00095 {ECO:0000313|EMBL:QDP38783.1};
OS Radiobacillus deserti.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Radiobacillus.
OX NCBI_TaxID=2594883 {ECO:0000313|EMBL:QDP38783.1, ECO:0000313|Proteomes:UP000315215};
RN [1] {ECO:0000313|EMBL:QDP38783.1, ECO:0000313|Proteomes:UP000315215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TKL69 {ECO:0000313|EMBL:QDP38783.1,
RC ECO:0000313|Proteomes:UP000315215};
RA Li J.;
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DCK/DGK family.
CC {ECO:0000256|ARBA:ARBA00007420}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP041666; QDP38783.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A516KBK9; -.
DR KEGG; aqt:FN924_00095; -.
DR OrthoDB; 9776634at2; -.
DR Proteomes; UP000315215; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019136; F:deoxynucleoside kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01673; dNK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002624; DCK/DGK.
DR InterPro; IPR031314; DNK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10513; DEOXYNUCLEOSIDE KINASE; 1.
DR PANTHER; PTHR10513:SF15; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL; 1.
DR Pfam; PF01712; dNK; 1.
DR PIRSF; PIRSF000705; DNK; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW Kinase {ECO:0000313|EMBL:QDP38783.1};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000315215};
KW Transferase {ECO:0000313|EMBL:QDP38783.1}.
FT DOMAIN 15..214
FT /note="Deoxynucleoside kinase"
FT /evidence="ECO:0000259|Pfam:PF01712"
FT ACT_SITE 90
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-1"
FT BINDING 19..27
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
FT BINDING 43
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 55
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 66
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 91
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 96
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 150..154
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
FT BINDING 159
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
SQ SEQUENCE 226 AA; 26752 MW; E761CDE14A66C646 CRC64;
MNKRERYNIP HDSIITIAGT VGVGKSTLTN SLANALNFKT SFEKVDTNPY LDKFYADFER
WSFHLQIYFL AERFKEQKRM FEYGGGFIQD RSIYEDTGIF AKMHYEKGTM NAVDYETYTS
LFEAMVMTPY FPHPDLLIYL EGSFDDIIGR IRERGRPMEQ QTPLSYWEEM FHRYDNWINS
FNACPVLRLN IADYDLVHDE TSIDYILEKV GHFIQQSRKW KSGQLT
//
