ID A0A517KVP1_9PEZI Unreviewed; 1333 AA.
AC A0A517KVP1;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=Amino acid permease/ SLC12A domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=FKW77_000428 {ECO:0000313|EMBL:QDS67442.1};
OS Venturia effusa.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Venturiales; Venturiaceae; Venturia.
OX NCBI_TaxID=50376 {ECO:0000313|EMBL:QDS67442.1, ECO:0000313|Proteomes:UP000316270};
RN [1] {ECO:0000313|EMBL:QDS67442.1, ECO:0000313|Proteomes:UP000316270}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=albino {ECO:0000313|Proteomes:UP000316270};
RA Young C.A., Cox M.P., Ganley A.R.D., David W.J.;
RT "Finished genome of Venturia effusa.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP042185; QDS67442.1; -; Genomic_DNA.
DR STRING; 50376.A0A517KVP1; -.
DR Proteomes; UP000316270; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR PANTHER; PTHR11827:SF72; GH08340P; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000316270};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 112..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 515..535
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 542..558
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 118..593
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 606..691
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT DOMAIN 1266..1329
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 64..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1033..1121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1149..1248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..91
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1046..1060
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1066..1084
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1160..1175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1215..1241
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1333 AA; 146693 MW; 949F3ADB9EA1A180 CRC64;
MNREQPVGRP LPRSHSNFQG GTATDAHDQL GRRWSIFRTT PSPRDEAHST GFFYHLFRRS
NSDERQHVRS RTSSRHRSAS KEPLLGKRRN SRDVRPRLKS TVNQNGPAGA KLGTFAGVFV
PTTLNVLSIL MFLRFGFILG QSGVLGMLAM LIACYAINLL TTMSISAIAT NGTVRGGGAY
YLLSRSLGPE FGGSIGMVFY LGCVFNTGMN AVGLIDCLRY NFGATNGGWS QWLPDGFWFN
YLWATVVLVF CTAVCLAGSG LFARASNGLL VILLVATFSI PISTIFMSPF ESKRLGIEYT
GPSMDTFKGN LMPHFTKGAD GSQLKGRETW QDLFGILFPA TGGIFAGASM SGDLKHPSKA
IPKGTLYGLL MTFFSYTIVI LAMGATITRT SFYHNVNVIQ DVNVSGVVVL LGEIATSLFS
SLMGVIGSAK LLQALARDKL IPGLSIFGQG TKNGDEPTYA IIVTYAVAQL TMLADINQIA
SFVTMTYLLT FIITNLACFL LTIGSAPNFR PSFHFFNWQT AFFGTLVSGA VMIFVDRLYA
TMSVGIMAFI FLLIHYTTPP KSWGDVSQSL IYHQVRKYLL RLRSDHIKFW RPSVLLLVND
PRRQYKLIQF CNSLKKGGLF ILGHVIVTQD FSGAVAEAKQ QQSNWQKYID FSKIKAFINI
SISPAVEWGA RNVVLGAGLG GMRPNIVVMG FFNLNDLRHS QTLVDIPSPQ PSRPASVRSI
ELKGPKDLKS PKLKDPKKRV KKDLESLRGR LPTDINRSEG AIGACSYMTV LEDMVLRLQI
NVAIGKGFQE LELPSPKPTK IERAMSWLGW KEIDENDNTK KFIDLWPIQM SAEICADGGD
GSESKKAMLT SNFDTYTLIL QLGCILDTVP SWKRAFNVRV CVFVEYESDV EEERGRVTSL
LNNLRIQAEV LVFWLASGSL KTYEVVVNGK RGNSYSQAMS DVNETLEDEE WWDDVQKLRG
MKGKLSAVEE LAEMENILDS TASWPTSSYQ YGRQVESNVV KFEGLRKMMR KAKRRASNGT
QFRVSMKASS STFDHDLHMG HPAYDSASES ASSSGENDSD DSAVSEADAD DYKSDTEVPK
SPIKRSKSVG DSLRPLFLRD RSGKASSSRP ATPMTPPLLP LASKKDTVVP EVSLIDTTNK
PQPLRRDVKT EALSPQIEPK RPSNLRQQSF PRFTSRPVPA TKIATEENDL GGRSIMFSDG
PSPPVKGDPR QSIYAVSESR PTRQPFSDPS SASSSNPTPP SGTPASGFPA LGAIPLTFND
LPCRAQHLIL NELINQNSSE TCTLMTTLPS PVLGTCESEV ESVRYLSDLE VLCQGLPPVL
LVHSNSMTVT MNL
//
