ID A0A540L327_MALBA Unreviewed; 1100 AA.
AC A0A540L327;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Histone-lysine N-methyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=C1H46_033540 {ECO:0000313|EMBL:TQD80870.1};
OS Malus baccata (Siberian crab apple) (Pyrus baccata).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Malus.
OX NCBI_TaxID=106549 {ECO:0000313|EMBL:TQD80870.1, ECO:0000313|Proteomes:UP000315295};
RN [1] {ECO:0000313|EMBL:TQD80870.1, ECO:0000313|Proteomes:UP000315295}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Shandingzi {ECO:0000313|Proteomes:UP000315295};
RC TISSUE=Leaves {ECO:0000313|EMBL:TQD80870.1};
RA Chen X.;
RT "Sequencing of a Wild Apple (Malus baccata) Genome Unravels the Differences
RT Between Cultivated and Wild Apple Species Regarding Disease Resistance and
RT Cold Tolerance.";
RL G3 (Bethesda) 9:1785-1793(2019).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TQD80870.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; VIEB01000791; TQD80870.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A540L327; -.
DR STRING; 106549.A0A540L327; -.
DR Proteomes; UP000315295; Unassembled WGS sequence.
DR GO; GO:0048188; C:Set1C/COMPASS complex; IEA:UniProt.
DR GO; GO:0140993; F:histone modifying activity; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR GO; GO:0051171; P:regulation of nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0022414; P:reproductive process; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd15662; ePHD_ATX1_2_like; 1.
DR CDD; cd15494; PHD_ATX1_2_like; 1.
DR CDD; cd20142; PWWP_AtATX1-like; 1.
DR CDD; cd10518; SET_SETD1-like; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.30.160.360; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR041956; ATX1/2_ePHD.
DR InterPro; IPR042010; ATX1/2_PHD.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR003889; FYrich_C.
DR InterPro; IPR003888; FYrich_N.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF140; HISTONE-LYSINE N-METHYLTRANSFERASE ATX2; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF05965; FYRC; 1.
DR Pfam; PF05964; FYRN; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00542; FYRC; 1.
DR SMART; SM00541; FYRN; 1.
DR SMART; SM00249; PHD; 2.
DR SMART; SM00293; PWWP; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS51543; FYRC; 1.
DR PROSITE; PS51542; FYRN; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000315295};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 317..380
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT DOMAIN 632..683
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 688..813
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 936..1054
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 1060..1076
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 50..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 151..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..75
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1100 AA; 123938 MW; 493A53A48D653057 CRC64;
MAFPLKHQND DASTPLRYLS LNHVYSATSP CVSASGSSNV MSKKVKARKL DDFDDGNGSG
NDGDQNLQKP SPKPSIVNVY SRRAKRPRHC SSFFDALLAR NEPAEVKIEE VEIDDVDGEF
ERVSETKKKR KLGFNELLKL GVDSSILSNL EGPRLRDSRS NPKLVGSKKG EKLRPKKRNS
SANCEKILSD SPSVKKWVGL SFNDVNPKTF IGLQCKASSL SIGHWMLIGI RAALWVTTLT
LIDIMYCSYH FHSIEYEDAD EEDLLLSSER LKFYISREEM ESLNLSCSPK STNSDVYDYN
EMVVLAASLD DCQELEPGDI IWAKLTGYAM WPAIVVDESL IGDRKGLSKT LGGNSVPVQF
FGTHDFARIK VKQAISFLKG LLSSFHLKCK KPGFIKSLEE AKMYLNEQKL PRTMLRLQNG
INIDERESIS GEDEVSADSG EGCFDDAGIP RTLDYLGTSP FVIGDLQIIN LGKIVRDSEC
FQDEKYIWPE GYTALRKFTS ITDPSVLALY KMEVLRDTES NIRPLFKVSL DTGEQFKGST
PSACWNKIYK RITKAQNNSF GGSNANAEGR LEGTYKSGSH MFGFSIPEVA KRIQRLSKSR
LSSKLPKCKL ASRRYRDAPV GYRPVRVDWK DLDKCSVCHM DEEYENNLFL QCDKCRMMVH
ARCYGELEPV GGVLWLCNLC RPGAPEPPPP CYLCPVIGGA MKPTTDGRWA HLACAIWIPE
TCLSDVKRME PIDGLSRINK DRWKLLCSIC GVSYGACIQC SNHTCCVAYH PLCARAAGLC
VELEDEDRLH LLSVDDDEVE QCIRLLSFCK KHRQPTNDRS AADNRISRTV RRCSEYIPPS
NPSGCARTEP YNYFCRRGRK EPEAIAAASL KRLFVENQPY LVGGYTQHQL SSNSQPPNGS
RFCCSLQRLK ASQLDAPNDI LSMSEKYKYM RDTFRKRLAF GKSGIHGFGI FAKHPHRAGD
MVIEYTGELV RPPVADRREH FIYNSLVGAG TYMFRIDDER VIDATRAGSI AHLINHSCEP
NCYSRVISVN NDEHIIIFAK RDIKRWEELT YDYRFFSIDE QLACYCGFPR CQGVVNDVES
EERATKLCAP RSELIDWSGE
//
