ID   A0A542SMB4_9MICO        Unreviewed;       343 AA.
AC   A0A542SMB4;
DT   16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=4-hydroxy-tetrahydrodipicolinate synthase {ECO:0000313|EMBL:TQK75769.1};
GN   ORFNames=FB389_0404 {ECO:0000313|EMBL:TQK75769.1};
OS   Rarobacter incanus.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Rarobacteraceae;
OC   Rarobacter.
OX   NCBI_TaxID=153494 {ECO:0000313|EMBL:TQK75769.1, ECO:0000313|Proteomes:UP000316181};
RN   [1] {ECO:0000313|EMBL:TQK75769.1, ECO:0000313|Proteomes:UP000316181}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10596 {ECO:0000313|EMBL:TQK75769.1,
RC   ECO:0000313|Proteomes:UP000316181};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DapA family.
CC       {ECO:0000256|PIRNR:PIRNR001365}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TQK75769.1}.
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DR   EMBL; VFNV01000001; TQK75769.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A542SMB4; -.
DR   OrthoDB; 9778880at2; -.
DR   Proteomes; UP000316181; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   CDD; cd00408; DHDPS-like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002220; DapA-like.
DR   PANTHER; PTHR12128:SF73; 4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE; 1.
DR   PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR   Pfam; PF00701; DHDPS; 1.
DR   PIRSF; PIRSF001365; DHDPS; 1.
DR   SMART; SM01130; DHDPS; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW   Reference proteome {ECO:0000313|Proteomes:UP000316181}.
FT   REGION          319..343
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        326..343
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         49
FT                   /ligand="pyruvate"
FT                   /ligand_id="ChEBI:CHEBI:15361"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ   SEQUENCE   343 AA;  36024 MW;  66718068E7AC6968 CRC64;
     MTVSILGPLT AYLPTPRDES GKLIASTMES LIEGALEYGA TAFGVVSGTG GATYLSRSVR
     RRVIKLTIAK AHGRAAILVG VSSFATAEVA ANVDEAAQAG ADAVLLQPFA SQQLRAEEVL
     GLYRDVATVS SLPVIIDNNP TTTHYRISTS ELARLVPIKG IVGVKDSAAT ASEARQRRER
     VLGALSPRTA RRTEYGFATS SFGAQALIDG ADTWHSAVAA VLPEYCGAIA YAATNRRRAE
     ARQMQRALAP LGMLSEQWGA IRVVHAIGTL RGLDMGVPPR PLLPLPREAN ALVRVTLNGL
     RVDDDLLAAT RDAAAARAAS HAQVSRDGAD SVSPTGGRHT TGR
//