ID A0A543NIU2_9ACTN Unreviewed; 445 AA.
AC A0A543NIU2;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Na+/H+-dicarboxylate symporter {ECO:0000313|EMBL:TQN31670.1};
GN ORFNames=FHX37_1589 {ECO:0000313|EMBL:TQN31670.1};
OS Haloactinospora alba.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Haloactinospora.
OX NCBI_TaxID=405555 {ECO:0000313|EMBL:TQN31670.1, ECO:0000313|Proteomes:UP000317422};
RN [1] {ECO:0000313|EMBL:TQN31670.1, ECO:0000313|Proteomes:UP000317422}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45015 {ECO:0000313|EMBL:TQN31670.1,
RC ECO:0000313|Proteomes:UP000317422};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TQN31670.1}.
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DR EMBL; VFQC01000001; TQN31670.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A543NIU2; -.
DR OrthoDB; 9766690at2; -.
DR Proteomes; UP000317422; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0046942; P:carboxylic acid transport; IEA:UniProt.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR PANTHER; PTHR42865:SF7; PROTON_GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000317422};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 407..445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 445 AA; 46242 MW; 2FFD59D977554692 CRC64;
MSQRQSEKTL WRRYLEFPLI WKLAIGLVGG AIAGLAIGEP VTVIEPLGDI FLRLLQMMVM
PLIVTTLITG VSSVTPARLG RIGTKVFAFY LVTSAFAITF GLVLALAVSP GSGLSMPSGG
KEPQEAPPLS ETLLGIVPEN PVAALVEGNV LAVMFLSVIA GIALAFMRGS DSERIRELGD
LLRRGVDGAV ELTFLVIRGV LQYAPVGVFA LIAVVMAETG VDALLPLAKL TGVVYGAVAL
QIVVYAVLML VFRIGVRRFF NAAKDPMVTG FVTRSSSGTL PVSTRAAEKL GVRDSVYSFT
LPLGANINMD GTAIYVGTAT VFVANVQGVE LTVGQLATVV LVGVLASVGT AGVPGAGLIM
LSMTVSQTGL SFAPVALVAG IDAILDMVRT MCNVTGDLAG TRIIARTEPG MLRDTDDSSE
PDVPTEASSS QETTGGNGSG NVDQS
//
