ID A0A545AK72_9ACTN Unreviewed; 506 AA.
AC A0A545AK72;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=rRNA small subunit methyltransferase B {ECO:0000313|EMBL:TQS41671.1};
GN ORFNames=FL583_28690 {ECO:0000313|EMBL:TQS41671.1};
OS Cryptosporangium phraense.
OC Bacteria; Actinomycetota; Actinomycetes; Cryptosporangiales;
OC Cryptosporangiaceae; Cryptosporangium.
OX NCBI_TaxID=2593070 {ECO:0000313|EMBL:TQS41671.1, ECO:0000313|Proteomes:UP000317982};
RN [1] {ECO:0000313|EMBL:TQS41671.1, ECO:0000313|Proteomes:UP000317982}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A-T 5661 {ECO:0000313|EMBL:TQS41671.1,
RC ECO:0000313|Proteomes:UP000317982};
RA Suriyachadkun C.;
RT "Cryptosporangium phraense sp. nov., isolated from plant litter.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RsmB/NOP family. {ECO:0000256|ARBA:ARBA00007494,
CC ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TQS41671.1}.
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DR EMBL; VIRS01000024; TQS41671.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A545AK72; -.
DR InParanoid; A0A545AK72; -.
DR OrthoDB; 9810297at2; -.
DR Proteomes; UP000317982; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR018314; Fmu/NOL1/Nop2p_CS.
DR InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR InterPro; IPR023267; RCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR22807:SF61; NOL1_NOP2_SUN FAMILY PROTEIN _ ANTITERMINATION NUSB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR Pfam; PF01189; Methyltr_RsmB-F; 1.
DR PRINTS; PR02008; RCMTFAMILY.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS01153; NOL1_NOP2_SUN; 1.
DR PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01023}; Reference proteome {ECO:0000313|Proteomes:UP000317982};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU01023};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01023};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01023}.
FT DOMAIN 204..501
FT /note="SAM-dependent MTase RsmB/NOP-type"
FT /evidence="ECO:0000259|PROSITE:PS51686"
FT REGION 1..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..67
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 432
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 309..315
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 334
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 358
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 379
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ SEQUENCE 506 AA; 50158 MW; DCA9F5E04D4BA75C CRC64;
MGDSETAAAL AADNARPGVD LAARPGRITP DELAAEVQAE LGRTPRHPKS PPPPTDAPTP
VGDAPPADGA PPADGAAPAD GAPPADGAAV ADGSAPAGSA TPADAVSDGA APVDGAAPVD
GAPPRDGAAP AEGAAPVDGS APATDERTSA PTDRLPADGP STASTAAPAD ASTAESPGTP
AVAPADGAVP ASAGQPTPAT AEQPAPAAAE QPSPAAAGQP APAAAEQPAP AAAEQPSPAT
PSAPAPADDD TLLGRWSPVA VKLPEGAPGD VKAIADGRAH VQDEGSQLCA WTLATAPLTG
PDTTWLDLCA GPGGKAGLLG SIAAQKDAHL TAVEVTEHRA ELVEKAVTDL PVTVLNADGR
DVGTHPDLPE NGFDRVLVDA PCTGLGALRR RPEARWRREP SDVPALAKLQ RELLLAAIRA
ARPGGLVAYV TCSPHLAETR VLVADVCRRT NAEPIDVRMV PEAARAAGPA PKGSPVSAAA
LQLWPHRHGT DAMFLCLLRK PTNPHD
//
