ID   A0A545VHF8_9HYPO        Unreviewed;      1051 AA.
AC   A0A545VHF8;
DT   16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2019, sequence version 1.
DT   22-FEB-2023, entry version 11.
DE   SubName: Full=Cytoskeleton assembly control protein Sla2 {ECO:0000313|EMBL:TQW01163.1};
GN   ORFNames=IF1G_01094 {ECO:0000313|EMBL:TQW01163.1};
OS   Cordyceps javanica.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Cordycipitaceae; Cordyceps.
OX   NCBI_TaxID=43265 {ECO:0000313|EMBL:TQW01163.1, ECO:0000313|Proteomes:UP000315783};
RN   [1] {ECO:0000313|EMBL:TQW01163.1, ECO:0000313|Proteomes:UP000315783}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IJ1G {ECO:0000313|EMBL:TQW01163.1,
RC   ECO:0000313|Proteomes:UP000315783};
RX   PubMed=31273397;
RA   Lin R., Zhang X., Xin B., Zou M., Gao Y., Qin F., Hu Q., Xie B., Cheng X.;
RT   "Genome sequence of Isaria javanica and comparative genome analysis
RT   insights into family S53 peptidase evolution in fungal entomopathogens.";
RL   Appl. Microbiol. Biotechnol. 103:7111-7128(2019).
CC   -!- SIMILARITY: Belongs to the SLA2 family.
CC       {ECO:0000256|ARBA:ARBA00010135}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TQW01163.1}.
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DR   EMBL; SPUK01000001; TQW01163.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A545VHF8; -.
DR   STRING; 43265.A0A545VHF8; -.
DR   Proteomes; UP000315783; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR   GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR   CDD; cd17007; ANTH_N_Sla2p; 1.
DR   Gene3D; 1.25.40.90; -; 1.
DR   Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR   InterPro; IPR011417; ANTH_dom.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR008942; ENTH_VHS.
DR   InterPro; IPR035964; I/LWEQ_dom_sf.
DR   InterPro; IPR002558; ILWEQ_dom.
DR   InterPro; IPR030224; Sla2_fam.
DR   PANTHER; PTHR10407; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR   PANTHER; PTHR10407:SF15; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR   Pfam; PF07651; ANTH; 1.
DR   Pfam; PF01608; I_LWEQ; 1.
DR   SMART; SM00273; ENTH; 1.
DR   SMART; SM00307; ILWEQ; 1.
DR   SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR   SUPFAM; SSF89009; GAT-like domain; 1.
DR   SUPFAM; SSF109885; I/LWEQ domain; 1.
DR   PROSITE; PS50942; ENTH; 1.
DR   PROSITE; PS50945; I_LWEQ; 1.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000315783}.
FT   DOMAIN          8..137
FT                   /note="ENTH"
FT                   /evidence="ECO:0000259|PROSITE:PS50942"
FT   DOMAIN          809..1051
FT                   /note="I/LWEQ"
FT                   /evidence="ECO:0000259|PROSITE:PS50945"
FT   REGION          279..307
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          338..360
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          984..1037
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1051 AA;  118858 MW;  6CBD025C95C2243A CRC64;
     MSTLRTAEHT KTDQELAISI KKATNADEIS PKRKHVRACI VYTWDHRSSL AFWSGIKVQP
     IMADEVQTFK ALITIHKVLQ EGHPSALKEA MANRGWIDGL NRGMAGEGVR GYGPLIREYV
     YFLLAKLSFH QAHPEFNGTF EYEEYISLKA INDPNEGYET ITDLMVLQDK IEQFQKLVFS
     HFRNVGNNEC RIAALVPLVH ESYGIYKFIT SMLRALHTIT GDDDALQPLR ERYDAQHYRL
     VKFYYECSNL RYLTSLINIP KLPHDPPNLL AEDENAPALP ARPKQEIERQ PTPVQEPKSA
     EPDEISDFWK SELDRQNREY EEQQRVLEQR QQAQLQAQQQ AQMQAQRDFD EQQRRLAEQQ
     QREQEALLAQ QAQWQTQGRL AELERENLNA RSRFEQDQLM LQKYDQRVKA LEGELTQLQN
     NYGQQLTSKD EQIRALQEQV NTWRTKYEAL AKLYSQLRTE HLDLLQKFKA VQLKAASAQE
     AIDRREKLER EIKTKNLELA DMIRERDRAM HDKDRLSGSN KDELEKLKRE LRIANDRADN
     LERSKGNELS TMLSKYNREM SDLEEALRTK SRALDDAHSK LRDGSSDLEQ LLRDKEEELE
     VYKAGMDQTL IELNDLKQNQ GSNDEVLDSQ LDAIIMANLD KINDIIDSVL QAAIGRVDDA
     LYELDSTMQA GNQNASPAYV LSQIEKAAAS AMEFATSFNN FIADGPNSTH AELIKSVNVF
     SGAMADVCSN TKGLTRLATD DRKTDSLMNG ARQSAMASVQ FFRGLQSFRL EGMDQVQKTD
     VVINSSTDVQ MNLQKLNKLV EGFAPGFGKF ANNKGDLGDI VDAELSKAAD AIAAAAARLA
     KLKNKPRDGY STYELKVNDS ILDAATAITN AIGELIRAAT VTQQEIVQAG KGSSSRTAFY
     KKNNRWTEGL ISAAKAVASS TNTLIETADG VLSKRNSPEQ LIVASNDVAA STAQLVAASR
     VKAGFMSKNQ DKLEQASKAV GAACRALVRQ VQNMIKERSQ EEDQVDYSKL GHHEFKVREM
     EQQVEILQLE NALAAARHRL GEMRKISYQE E
//