ID A0A547Q7A2_9RHOB Unreviewed; 443 AA.
AC A0A547Q7A2;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Insulinase family protein {ECO:0000313|EMBL:TRD22254.1};
GN ORFNames=FEV53_05905 {ECO:0000313|EMBL:TRD22254.1};
OS Palleronia caenipelagi.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Palleronia.
OX NCBI_TaxID=2489174 {ECO:0000313|EMBL:TRD22254.1, ECO:0000313|Proteomes:UP000318590};
RN [1] {ECO:0000313|EMBL:TRD22254.1, ECO:0000313|Proteomes:UP000318590}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBTF-M29 {ECO:0000313|EMBL:TRD22254.1,
RC ECO:0000313|Proteomes:UP000318590};
RA Yoon J.-H.;
RT "Paenimaribius caenipelagi gen. nov., sp. nov., isolated from a tidal
RT flat.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TRD22254.1}.
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DR EMBL; VFSV01000007; TRD22254.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A547Q7A2; -.
DR OrthoDB; 9811314at2; -.
DR Proteomes; UP000318590; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR43690; NARDILYSIN; 1.
DR PANTHER; PTHR43690:SF17; PROTEIN YHJJ; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000318590};
KW Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..443
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5021795679"
FT DOMAIN 32..177
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 185..368
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 443 AA; 49016 MW; 57E66C5CFA28F388 CRC64;
MFRFATALTL AAAVPATAAE VTDFTLENGM EVVVIEDHRA PVVVHMVWYK VGAADETAGV
SGVAHYLEHL MFKGTDTLEP GEFSQVVEAQ GGSDNAFTSF DYTAYHQRVA ADRLGLMMEM
EADRMRNLRL DDRDIATELR VVQEERNQRI ENDPGALFAE QRDAAQYLNH PYGRPVIGWM
DEVESLQLED ALSFYETYYA PNNAILIVAG DVTPDEVRAL AEEHYGPVPP TPDLPERTRP
QEPPQLVERR LVYEDPKVAQ PYVIRSYLAP ERNPGDQKTA AALTILAEVL GNGQSSELAQ
RLQFGTGEAL YASAFYSGTT LDRTTFGLVM VPAPGVSLPD AEAALDRAVT EFLDEGVDPD
QLERIKTRIR AAEIYEADSA RELANRYGRA LSIGLTLDDV ESWPDELRAV TGEDVIAAAR
DVFDRRNAVT GYLKAPEAQE MTQ
//
