ID A0A553NNY3_TIGCA Unreviewed; 741 AA.
AC A0A553NNY3;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=SCP2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=TCAL_07644 {ECO:0000313|EMBL:TRY67110.1};
OS Tigriopus californicus (Marine copepod).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC Hexanauplia; Copepoda; Harpacticoida; Harpacticidae; Tigriopus.
OX NCBI_TaxID=6832 {ECO:0000313|EMBL:TRY67110.1, ECO:0000313|Proteomes:UP000318571};
RN [1] {ECO:0000313|EMBL:TRY67110.1, ECO:0000313|Proteomes:UP000318571}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=San Diego {ECO:0000313|EMBL:TRY67110.1,
RC ECO:0000313|Proteomes:UP000318571};
RX PubMed=29988158; DOI=.1038/s41559-018-0588-1;
RA Barreto F.S., Watson E.T., Lima T.G., Willett C.S., Edmands S., Li W.,
RA Burton R.S.;
RT "Genomic signatures of mitonuclear coevolution across populations of
RT Tigriopus californicus.";
RL Nat. Ecol. Evol. 2:1250-1257(2018).
CC -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC {ECO:0000256|ARBA:ARBA00005005}.
CC -!- SUBCELLULAR LOCATION: Peroxisome {ECO:0000256|ARBA:ARBA00004275}.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TRY67110.1}.
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DR EMBL; VCGU01000011; TRY67110.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A553NNY3; -.
DR STRING; 6832.A0A553NNY3; -.
DR EnsemblMetazoa; TCAL_07644-PA_mrna; TRY67110.1; TCAL_07644.
DR OMA; WATKVHT; -.
DR OrthoDB; 2140828at2759; -.
DR UniPathway; UPA00659; -.
DR Proteomes; UP000318571; Chromosome 4.
DR GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR CDD; cd03448; HDE_HSD; 1.
DR CDD; cd05353; hydroxyacyl-CoA-like_DH_SDR_c-like; 1.
DR Gene3D; 1.10.287.4290; -; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR002539; MaoC-like_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR InterPro; IPR003033; SCP2_sterol-bd_dom.
DR InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR45024; DEHYDROGENASES, SHORT CHAIN; 1.
DR PANTHER; PTHR45024:SF2; SCP2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00106; adh_short; 1.
DR Pfam; PF01575; MaoC_dehydratas; 1.
DR Pfam; PF02036; SCP2; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SMART; SM00822; PKS_KR; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF55718; SCP-like; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 2.
DR PROSITE; PS00061; ADH_SHORT; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Reference proteome {ECO:0000313|Proteomes:UP000318571}.
FT DOMAIN 477..585
FT /note="MaoC-like"
FT /evidence="ECO:0000259|Pfam:PF01575"
FT DOMAIN 634..735
FT /note="SCP2"
FT /evidence="ECO:0000259|Pfam:PF02036"
SQ SEQUENCE 741 AA; 80394 MW; EF5B0FD0E67F4179 CRC64;
MSIRFDNRVA VVTGAGGGLG KAYALLLASR GASVVVNDLG GSRSGEGQSS KAADEVVSEI
RNKGGKAVAN YDSVENGEAV IKTALDNFGR IDIVINNAGI LRDRSIARTA DSDWDLVHRV
HLRGAFQVTR AAWPHMKKQK YGRIVNTSSV AGIFGNFGQA NYSAAKAGLL GFTNTLAIEG
ERSGIQANII VPMAASRLTQ DILPPELFDG LKPELIAPVV AWMCHEDCPD TGSIIEAAGG
WAGKYRWQRS QGTLLMDDLS ENITPERVRE RWAQIVDMQG GDFPTSNQGA TMDLVGKMEK
LTSSPDSTQI QGDLMSAIGF KSQPFLYNFD HRDVILYALA VGASTENHHG LKYLYEGNPN
FSALPSFGVM PGFGSFVGLI NGDVPGLEID LSKVLHGEQY TEMVSTRLPT EGSLESTFQI
QAILDKGSGA VLLVEVLTKD QVTQETIVKN QMSVFVVGSG GFNGPRSSEH LIPTEKNPSH
APDWEMTYQT NIDQAALYRL CGDANPLHID PSFSGISGFK KPILHGLCSY GIAARQIVDE
VCQGDPGRVK AIKARFAKPV IPGQTLVTKA WKINNEKISF SCVVKETGQE CLNGGWIILR
SYQDDKQSDD GGGRKQSPDM EQKLGTTLKS DVVFQAMERR LKAKPDMVNK VRAVFHWIIT
NSQGKPASHW TVDLKNTPGS ITQGAHGTPD CTLTIFDDDM VQMVEGNLKP QTAFMKGKLK
VKGNIMLTQK LQDLIGDHSK L
//
